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Crystallization of Biological Macromolecules, by Alexander McPherson. 1999. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press. Hardcover, 586 pp. $97

Published online by Cambridge University Press:  01 July 1999

Adrian R. Ferré-D'Amaré
Adrian R. Ferré-D'Amaré
Affiliation:
Department of Molecular Biophysics and Biochemistry, Yale University, P.O. Box 208114, New Haven, Connecticut 06520-8114, USA; e-mail: ferre@csb.yale.edu
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Abstract

“Crystallization, as applied to proteins, was long held in high esteem, but hardly considered science.” I quote from the preface to Alexander McPherson's new survey of the field, Crystallization of Biological Macromolecules. Years ago, McPherson's previous monograph (Preparation and Analysis of Protein Crystals, 1982, Wiley) introduced me to the subject. The growth of knowledge about protein crystallization in the past 17 years is vividly illustrated by comparison of the two books. The slim old volume contained a single chapter on experimental procedures for protein crystallization. In contrast, the 1999 book has three chapters on experimental issues, plus several chapters that review the emerging understanding of the physical chemistry of macromolecular crystallization.

Type
BOOK REVIEW
Information
RNA , Volume 5 , Issue 7 , July 1999 , pp. 847 - 848
Copyright
© 1999 RNA Society

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