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Grading the thalamus: how can an ‘Eph’ be excellent?

Published online by Cambridge University Press:  13 March 2007

Colenso M. Speer  and
Barbara Chapman
Colenso M. Speer
Affiliation:
Center for Neuroscience, University of California, Davis, USA
Barbara Chapman
Affiliation:
Center for Neuroscience, University of California, Davis, USA
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Abstract

The Eph family of receptor tyrosine kinases and their partner ligands, the ephrins, mediate cell–cell interactions in the developing nervous system. Signaling events between Eph receptors and ephrin ligands on interacting cells affect the growth, maturation, migration and connectivity of individual neurons and neural networks. Here we review the known roles of Eph–ephrin signaling in the development of the thalamus and its connections, and pose new questions for experimental study.

Keywords

Ephephrinthalamocorticalcorticothalamiccompartmentalization
Type
Review Article
Information
Thalamus & Related Systems , Volume 3 , Issue 3 , September 2005 , pp. 235 - 244
Copyright
2007 Cambridge University Press

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