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Mood Changes After Right-Hemisphere Lesions

Published online by Cambridge University Press:  02 January 2018

Sergio E. Starkstein ,
Robert G. Robinson ,
Marc A. Honig ,
Rajesh M. Parikh ,
John Joselyn  and
Thomas R. Price
Sergio E. Starkstein*
Affiliation:
Department of Psychiatry
Robert G. Robinson
Affiliation:
Department of Psychiatry and Neuroscience
Marc A. Honig
Affiliation:
Department of Psychiatry, Johns Hopkins University School of Medicine
Rajesh M. Parikh
Affiliation:
Department of Psychiatry, Johns Hopkins University School of Medicine
John Joselyn
Affiliation:
Department of Radiology
Thomas R. Price
Affiliation:
Department of Neurology, University of Maryland School of Medicine
*
∗Meyer 4-119, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, Maryland 21205, USA
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Abstract

Ninety-three patients with acute stroke lesions restricted to the right hemisphere were examined for the presence of mood changes. While 46 patients showed no mood changes, 19 were unduly cheerful, 17 had developed major depression, and 11 had developed minor depression. Although there were no significant between-groups differences in other demographic variables, neurological deficits, activities of daily living, cognitive impairment, or quality of social support, patients with major depression had a significantly higher frequency of familial history of psychiatric disorder and lesions of the parietal cortex than patients with either no mood change or major depression following left-hemisphere lesions. On the other hand, undue cheerfulness was significantly associated with lesions of the right frontal operculum. These findings suggest that major depression following right-hemisphere lesions may have a different aetiology and mechanism than major depression following left frontal or basal ganglia lesions.

Type
Papers
Information
The British Journal of Psychiatry , Volume 155 , Issue 1 , July 1989 , pp. 79 - 85
Copyright
Copyright © The Royal College of Psychiatrists 

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