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Respiratory Ventilation and Carbon Dioxide Levels in Syndromes of Depression

Published online by Cambridge University Press:  29 January 2018

J. Damas Mora
Affiliation:
Especialista em Psiquitria (Portugal), Lecturer in Psychiatry, University of Sheffield, Attached Worker of the MRC Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TD
L. Grant
Affiliation:
MRC Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TP
Patricia Kenyon
Affiliation:
MRC Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TP
M. K. Patel
Affiliation:
Visiting Biostatistican from the University of Illinois Medical Center
F. A. Jenner
Affiliation:
University of Sheffield; and Honorary Director of the Medical Research Council Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TP

Summary

The breathing rate and PCO2 in end-tidal air have been studied in controls and in patients with endogenous depression (retarded and non-retarded), with neurotic depression, and with schizophrenia. It has been shown that breathing rate goes up and PCO2 down in non-retarded and neurotic depression. Schizophrenia gives more anomalous results. The fact is emphasized that such changes must lead to alterations in pH and other variables. Studies showing some small chemical differences between these clinical entities and control subjects might therefore be explained by these findings.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1976 

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References

Abbate, E. H. & Viola, A. R. (1973) Estimation dc la pression parcial dc CO2 arterial por el valor dc PCO2 de fin de espiracion maxima. Medicina (Buenos Aires), 33, 522.Google Scholar
Braatöy, T. (1947) Der nervöse Sinn. Medicinsk Psykologi og Psykotcrapi. Oslo: Cappelen. (Cited by Skarbek, A. (1969), see below.) Google Scholar
Clausen, G. (1951) Respiratory movement in normal neurotic and psychotic subjects. Acta psychiat. Scand., Suppl 68. Copenhagen: Munksgaard.Google Scholar
Dubois, A. B., Fowler, R. C., Soffer, A. & Fenn, W. O. (1952) Alveolar CO2 measured by expiration into the rapid infrared gas analyser. J. appl. Physiol., 4, 526.Google Scholar
Eysenck, H. J. (1952) In The Scientific Study of Personality. New York.Google Scholar
Eysenck, H. J. & Eysenck, S. B. G. (1964) Manual of the Eysenck Personality Inventory. University of London Press.Google Scholar
Fenichel, O. (1946) Nature and classification of so-called psychosomatic phenomena. Jahrbuch der Psychoanalyse, 23.Google Scholar
Freud, S. (1917) Aus der Geschichte einer infantilen Neurose. Gesamte Werke, Bd 14. London: Imago.Google Scholar
Geisler, L. S. & Rost, H. D. (1972) Hyperkapnie. Stuttgart: Georg Thieme.Google Scholar
Goodman, L. S. & Gilman, A. (1971) The Pharmacological Basis of Therapeutics, p 188. London: MacMillan Co.Google Scholar
Hamilton, M. (1967) Development of a rating scale for primary depressive illness. Brit. J. soc. clin. Psychol., 6, 278.Google Scholar
Jurko, M., Jost, H. & Hill, T. S. (1952) Pathology of the energy system: an experimental clinical study of physiological adaptative capacities in psychoneurotics and in an early paranoid schizophrenic group. J. Psychol., 33, 183.CrossRefGoogle Scholar
Kiloh, L. G., Andrews, G., Neilson, M. & Bianchi, G. H. (1972) The relationship of the syndrome called endogenous and neurotic depression. Brit. J. Psychiat., 121, 143.Google Scholar
Lewis, A. J. (1970) The ambiguous word ‘anxiety’. Int. J. Psychiat., 9, 62.Google Scholar
Lewis, B. I. (1954) Chronic hyperventilation syndrome. J. Amer. med. Assoc., 155, 1204.CrossRefGoogle ScholarPubMed
Mapother, E. (1926) Discussion on manic-depressive psychosis. Brit. med. J., ii, 872.Google Scholar
Meili, E. (1948) Zur Pathophysiologic des Effortsyndroms. Helvet. med. Acta, 10, 440.Google Scholar
Paterson, A. S. (1934) The depth and rate of respiration in normal and psychotic subjects. J. Neurol. Psychopath., 14, 323.CrossRefGoogle ScholarPubMed
Paterson, A. S. (1935) respiratory rhythm in normal and psychotic subjects. J. Neurol. Psychopath., 16, 36.Google Scholar
Quint, H. (1972) Psychosomatische Syndrome. In Psychiatrie der Gegenwart, II/1, 2nd edition, p 587. Berlin: Springer.Google Scholar
Rossier, P. H. (1939) Die Atmungstetanie. Schweiz. med. Wschr., 69, 357.Google Scholar
Roth, M., Gurney, C., Garside, R. F. & Kerr, T. A. (1972) Studies in the classification of affective disorders. I. The relationship between anxiety states and depressive illness. Brit. J. Psychiat., 121, 147.CrossRefGoogle Scholar
Schwidder, W. (1956) Psychogene Störungen der Atemfunction inbesondere bei zwangsneurotischer Charakterstruktur. Zeitschrift psychosomatische Medizin, 2, 98.Google Scholar
Skarbek, A. (1969) The significance of variations in breathing behaviour in speech and at rest. Acta psychiat. Scand., 45, 217.Google Scholar
Skarbek, A. (1970) A psychophysiological study of breathing behaviour. Brit. J. Psychiat., 116, 637.CrossRefGoogle ScholarPubMed
Snaith, R. P., Ahmed, S. N., Mehta, S. & Hamilton, M. (1971) Assessment of the severity of primary depressive illness. Psychol. Med., 1, 143.CrossRefGoogle ScholarPubMed
Spielberger, C. D., Gorsuch, R. L. & Luschene, R. E. (1970) State-trait Anxiety Inventory (‘Self-Evaluation Questionnaire’). Consulting Psychologists Press Inc. Google Scholar
West, J. B. (1967) Ventilation/Blood Flow and Gas Exchange. Oxford: Blackwell Scientific Publications.Google Scholar
Wittkower, E. (1934) Further studies in the respiration of psychotic patient. J. merit. Sci., 80, 692.Google Scholar
Wundt, W. (1919) System der Philosophie, Vol II, p 175. Leipzig: Alfred Kroner Verlag.Google Scholar
Wyke, B. (1963) Brain Function and Metabolic Disorders. London: Butterworths.Google Scholar
Zar, J. H. (1974) Biostatistical Analysis. Englewood Cliffs, N.J.: Prentice-Hall Inc.Google Scholar
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