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Thyrotoxicosis and the Course of Manic-Depressive Illness

Published online by Cambridge University Press:  29 January 2018

S. A. Checkley*
Affiliation:
The Maudsley Hospital Institute of Psychiatry, De Crespigny Park, London, S.E.5

Summary

The effect of thyrotoxicosis upon the recurrence of manic-depressive psychoses has been studied by the use of a routine follow-up system. In this system 267 patients had three or more affective illnesses. Five of these patients had eight well-documented episodes of thyrotoxicosis. Only three of these eight episodes coincided with an affective illness, and in each case an alternative explanation for the association was available. These findings suggest that thyrotoxicosis has little effect upon the occurrence of a manic-depressive episode.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1978 

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References

Bluestone, H. (1957) Hyperthyroidism masquerading as functional psychosis. American Practitioner and Digest of Treatment, 8, 557–8.Google ScholarPubMed
Bursten, B. (1961) Psychoses associated with thyrotoxicosis. Archives of General Psychiatry, 4, 267–73.CrossRefGoogle ScholarPubMed
Clower, C. G., Young, A. J. & Kepas, D. (1969) Psychotic states resulting from disorders of thyroid function. Johns Hopkins Medical Journal, 124, 305–10.Google ScholarPubMed
Coulombe, P., Dussault, J. H. & Walker, P. (1977) Catecholamine metabolism in thyroid disease. II. Norepinephrine secretion in hyperthyroidism and hypothyroidism. Journal of Clinical Endocrinology and Metabolism, 44, 1185–9.CrossRefGoogle ScholarPubMed
Dunlap, M. F. & Moersch, F. P. (1935) Psychic manifestations associated with hyperthyroidism. American Journal of Psychiatry, 91, 1215–35.Google Scholar
Gibson, J. G. (1962) Emotions and the thyroid: a critical appraisal. Journal of Psychosomatic Research, 6, 693–116.CrossRefGoogle ScholarPubMed
Johnson, W. O. (1928) Psychosis and hyperthyroidism. Journal of Nervous and Mental Diseases, 67, 558–66.Google Scholar
Katzenelbogen, S. & Luton, F. H. (1935) Hyperthyroidism and psychobiological reactions. American Journal of Psychiatry, 91, 969–81.CrossRefGoogle Scholar
Kleinschmidt, H. J., Waxenberg, S. E. & Cuker, R. (1956) Psychophysiology and psychiatric management of thyrotoxicosis: a two-year follow-up. Journal of the Mount Sinai Hospital, New York, 23, 131–53.Google ScholarPubMed
Lidz, T. & Whitehorn, J. C. (1949) Psychiatric problems in a thyroid clinic. Journal of the American Medical Association, 139, 698701.Google Scholar
Martin, E. A. (1963) Thyrotoxic confusional state: a report of four cases. Irish Journal of Medical Science, 448, 187–96.Google Scholar
Michael, R. P. & Gibbons, J. L. (1965) Inter-relationships between the endocrine system and neuropsychiatry. International Review of Neurobiology, 5, 243302.CrossRefGoogle Scholar
Perris, C. (1975) The bipolar-unipolar dichotomy and the need for a consistent terminology. Neuropsychobiology, 1, 65–9.CrossRefGoogle ScholarPubMed
Rosser, R. (1976) Thyrotoxicosis and lithium. British Journal of Psychiatry, 128, 61–6.CrossRefGoogle ScholarPubMed
Spaulding, S. W., Burrow, G. N., Bermudez, F. & Himmeloch, J. M. (1972) The inhibitory effect of lithium on thyroid hormone release in both euthyroid and thyrotoxic patients. Journal of Clinical Endocrinology and Metabolism, 35, 905–11.CrossRefGoogle ScholarPubMed
Tunbridge, W. M. G., Evered, D. C., Hall, R., Appleton, D., Brewis, M., Clark, F., Grimley Evans, J., Young, E., Bird, T. & Smith, P. (1975) The prevalence of thyroid disorders in an English community. Thyroid Research, pp. 520–22, ed Robbins, J. L. Excerpta Medica, Amsterdam.Google Scholar
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