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Conclusion

Published online by Cambridge University Press:  06 August 2018

George Beaumont*
Affiliation:
Medical and Pharmaceutical Advisory Services, Stockport

Extract

Antidepressants, as the term is currently understood, were introduced into clinical practice in the late 1950s. The first of these was imipramine, shortly to be followed by amitriptyline and then by a series of related compounds - all chemically ‘tricyclics’. These subsequently became known as the ‘first-generation’ antidepressants; imipramine and amitriptyline in particular have since become the standards against which others have been compared.

Type
Research Article
Copyright
Copyright © 1993 The Royal College of Psychiatrists 

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