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Disturbance of Water and Sodium in a Manic-Depressive Illness

Published online by Cambridge University Press:  29 January 2018

J. L. Crammer
J. L. Crammer*
Affiliation:
Institute of Psychiatry, Denmark Hill, London SE5 8AZ
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Abstract

Specific questioning and frequent observation of a 69 year-old woman with cyclic bipolar manic-depressive illness showed that she had disturbances of thirst, appetite, bowel and bladder function and dramatic changes in body weight, in association with different phases of her mental illness. Examination of one manic phase under constant diet and inpatient control showed cardiovascular changes, sodium retention, body weight gain, with raised aldosterone secretion but steady vasopressin. There appears to be a sub-group of manic-depressive patients with evidence of disturbed hypothalamic functions as part of their mental illness, as shown particularly by changes in water and electrolyte metabolism.

Type
Papers
Information
The British Journal of Psychiatry , Volume 149 , Issue 3 , September 1986 , pp. 337 - 345
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

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