Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-10T07:25:29.586Z Has data issue: false hasContentIssue false

A Fatal Case of Pancytopenia Due to Levomepromazine

Published online by Cambridge University Press:  27 April 2018

N. Garzotto
Affiliation:
Istituto di Clinica Psichiatrica di Verona, Università di Padova, Policlinico, I-37100 Verona, Italy
L. Burti
Affiliation:
Istituto di Clinica Psichiatrica di Verona, Università di Padova, Policlinico, I-37100 Verona, Italy
M. Tansella
Affiliation:
Istituto di Clinica Psichiatrica di Verona, Università di Padova, Policlinico, I-37100 Verona, Italy

Summary

A fatal pancytopenia occurred in a patient with an history of depression with hypomanic rebounds, admitted for a manic episode and treated with levomepromazine, diazepam and lithium carbonate.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1976 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ananth, J. V., Lehmann, H. E. & Ban, T. A. (1970) Agranulocytosis associated with methotrimeprazine (Nozinan) administration: a report of three cases. Canadian Medical Association Journal, 102, 1286–7.Google ScholarPubMed
Ananth, J. V., Valles, J. V. & Whitelaw, J. P. (1973) Usual and unusual agranulocytosis during neuroleptic therapy. American Journal of Psychiatry, 130, 100–2.Google Scholar
Denber, H. C. B. (1970) An unusual case of chlorpro-mazine agranulocytosis. Diseases of the Nervous System, 31, 134–9.Google ScholarPubMed
Hollister, L. E. (1964) Complications from psychotherapeutic drugs. 1964. Clinical Pharmacology and Therapeutics, 5, 523–33.Google Scholar
McKinney, W. T. & Kane, F. J. (1967) Pancytopenia due to chlorpromazine. American Journal of Psychiatry, 123, 879–80.Google Scholar
Murphy, D. L., Goodwin, F. K. & Bunney, W. E. (1971) Leukocytosis during lithium treatment. American Journal of Psychiatry, 127, 135–7.CrossRefGoogle ScholarPubMed
Pisciotta, A. V. (1969) Agranulocytosis induced by certain phenothiazine derivates. Journal of the American Medical Association, 208, 1862–8.Google Scholar
Pisciotta, A. V. (1971) Drug-induced leukopenia and aplastic anemia. Clinical Pharmacology and Therapeutics, 12, 1343.Google Scholar
Pisciotta, A. V. (1974) The effect of chlorpromazine on peripheral leukocytes. In Drugs and Hematologic Reactions. The Twenty-ninth Hahnemann Symposium (eds Dimitrov, N. V. and Nodine, J. H.), pp 233–47. New York: Grune and Stratton.Google ScholarPubMed
Pretty, H. M., Gosselin, G., Colpron, G. & Long, L. A. (1965) Agranulocytosis: a report of 30 cases. Canadian Medical Association Journal, 93, 1058.Google ScholarPubMed
Shepherd, M., Lader, M. & Lader, S. (1968a) Central nervous system depressant drugs. In Side Effects of Drugs. Vol VI (eds Meyler, L. and Herxheimer, A.), pp 5193. Amsterdam: Excerpta Medica Foundation.Google Scholar
Shepherd, M., Lader, M. & Rodnight, R. (1968b) Clinical Psychophar-macology. London: The English Universities Press.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.