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Growth Hormone and other Responses to Clonidine in Patients with Endogenous Depression

Published online by Cambridge University Press:  29 January 2018

S. A. Checkley ,
A. P. Slade  and
E. Shur
S. A. Checkley
Affiliation:
Institute of Psychiatry, De Crespigny Park, London SE5 8AF; Honorary Consultant, Maudsley Hospital, London SE5 6AZ
A. P. Slade
Affiliation:
Institute of Psychiatry
E. Shur
Affiliation:
Institute of Psychiatry
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Summary

The growth hormone response to clonidine was significantly less in 10 drug-free patients with endogenous depression than in 10 normal subjects who were individually matched with the patients for age and sex. The hypotensive and sedative effects of clonidine in the two groups were similar. The findings may indicate a defect at central a adrenoceptors at least in neuroendocrine systems.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 138 , Issue 1 , January 1981 , pp. 51 - 55
Copyright
Copyright © The Royal College of Psychiatrists 

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