Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-13T01:32:54.322Z Has data issue: false hasContentIssue false
  • English
  • Français

Metronidazole and Alcoholism

Published online by Cambridge University Press:  29 January 2018

Julius Merry  and
Arnold Whitehead
Julius Merry
Affiliation:
Lambeth and St. Thomas's Hospitals, London, and West Park Hospital, Epsom, Surrey
Arnold Whitehead
Affiliation:
Warden, St. Luke's House, 25a Wincott Street, S.E.11
Get access Rights & Permissions [Opens in a new window]

Extract

Metronidazole (Flagyl) is an established and effective treatment of urogenital trichomoniasis. J. A. T. Taylor (1964) was using metronidazole to treat a husband and wife for this condition, when she observed the following. The husband, who was a chronic alcoholic, seemed to lose his craving for alcoholic drinks. Sometimes he experienced flushing of the face and shoulders and epigastric discomfort when he took metronidazole soon after alcohol, i.e. he experienced a disulfiram type reaction. The wife reported that alcohol drinks tasted unpleasant to her during therapy. Taylor then studied 53 alcoholic patients and concluded that metronidazole (i) decreased tolerance for alcohol, (ii) diminished craving for alcohol and (iii) produced an uncomfortable reaction to alcohol.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 114 , Issue 512 , July 1968 , pp. 859 - 861
Copyright
Copyright © Royal College of Psychiatrists, 1968 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ban, T. A., Lehmann, H. E., and Roy, P. (1966). Union Médicale du Canada, 95, 147.Google Scholar
Goodwin, D. W. (1967). Amer. J. Psychiat., 123, 1276.Google Scholar
Pearson, A. W., and Strassmann, H. (1965). Unpublished.Google Scholar
Rowe, A. J. E., and Atkinson, A. A. (1966). Unpublished.Google Scholar
Semer, J. M. et al. (1966). Amer. J. Psychiat., 123, 722.CrossRefGoogle Scholar
Taylor, J. A. T. (1964). Bull. Los Angeles Neurolog. Soc., 29, 158.Google Scholar
Willcox, D. R. C. et al. (1965). Brit. med. J., ii, 790.CrossRefGoogle Scholar
Semer, J. M. et al. (1966). Unpublished.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.