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Pharmacological and Clinical Problems of Lithium Prophylaxis

Published online by Cambridge University Press:  29 January 2018

M. Schou
Affiliation:
Psychopharmacology Research Unit, Aarhus University Psychiatric Institute, 8240 Risskov, Denmark
P. C. Baastrup
Affiliation:
Psychiatric Hospital, 2600 Glostrup, Denmark
P. Grof
Affiliation:
Psychiatric Research Institute, Prague, Czechoslovakia
P. Weis
Affiliation:
Pharmazeutisches Departement, J. R. Geigy AG, Basel, Switzerland
J. Angst
Affiliation:
Psychiatrische Universitätsklinik, CH-8008 Zürich, Lenggstrasse 31, Switzerland

Extract

Prophylactic maintenance treatment with lithium presents a number of features not shared by conventional therapies. Patients suffering from recurrent affective disorders are offered the possibility of avoiding further psychotic episodes (Baastrup and Schou, 1967; Angst et al., 1970), but the treatment also makes demands on doctors and patients.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1970 

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References

Allgén, L.-G. (1969). “Laboratory experience of lithium toxicity in man.” Acta psychiat Scand., Suppl. 207, 98104.CrossRefGoogle Scholar
Amdisen, A. (1967). “Serum lithium determinations for clinical use.” Scand. J. clin. Lab. Invest., 20, 104–8.CrossRefGoogle Scholar
Amdisen, A., and Schou, M. (1967). “Biochemistry of depression.” Lancet, i, 507.CrossRefGoogle Scholar
Amdisen, A., and Sjögren, J. (1968). “Lithium absorption from sustained release tablets (Duretter).” Acta pharmaceutica Suecia, 5, 465472.Google Scholar
Angst, J., Weis, P., Grof, P., Baastrup, P. G., and Schou, M. (1970). “Lithium prophylaxis in recurrent affective disorders.” Brit. J. Psychiat., 116, 604–14CrossRefGoogle Scholar
Baastrup, P. C., and Schou, M. (1967). “Lithium as a prophylactic agent. Its effect against recurrent depressions and manic-depressive psychosis.” Arch. gen. Psychiat., 16, 162–72.CrossRefGoogle Scholar
Bass, A. D., Yntema, C. L., Hammond, W. S., and Frazer, M. L. (1951). “Studies on the mechanism by which sulfadiazine affects the survival of the mammalian embryo.” J. Pharmacol, exp. Ther., 101, 362–7.Google Scholar
Bowman, J. A. (1967). “The application of resonance monochromators to the determination of lithium in blood serum by atomic absorption spectrophotometry.” Anal. Chim. Acta, 37, 465–71.CrossRefGoogle Scholar
Buhl, J., and Hansen, O. E. (1968). “Lithiumforgiftning. Meddelelse om 3 tilfælde.” Ugeskr. Leg., 130, 1525–26.Google Scholar
Goats, D. A., Trautner, E. M., and Gershon, S. (1957). “The treatment of lithium poisoning.” Aust. Ann. Med., 6, 1115.Google Scholar
Corcoran, A. C., Taylor, R. D., and Page, I. H. (1949). “Lithium poisoning from the use of salt substitutes.” J. Amer. med. Ass., 139, 685–8.CrossRefGoogle Scholar
Doerr, P., and Stamm, D. (1968). “Flammenphotometrische Lithiumbestimmung im Serum.” Klin. Chemie, 6, 178–82.Google Scholar
Fieve, R. R., and Platman, S. (1968). “Lithium and thyroid function in manic-depressive psychosis.” Amer. J. Psychiat., 125, 527–30.CrossRefGoogle Scholar
Fries, H. (1969). “Experience with lithium carbonate treatment at a psychiatric department in the period 1964–1967.” Acta psychiat. Scand., Suppl. 207, 41–3.Google Scholar
Gmelins Handbuch der anorganischen Chemie, ed. 8 (1960). “Lithium”. Ergänzungsband, System-Nummer 20. Weinheim: Verlag Chemie. Gonzales, R., and Lauter, H. (1968). “Zur Therapie manisch-depressiver Psychosen mit Lithiumsalzen.” Nervenarzt, 39, 1116.Google Scholar
Halberg, P., Dige-Petersen, H., Werdelin, O., Simonsen, J., and Rafaelsen, O. J. (1968). “Thyreoideapåvirkning under lithiumbehandling.” Ugeskr. Læg., 130, 1521–3.Google Scholar
Hanlon, L. W., Romaine, M., Gilroy, F. J., and Deitrick, J. E. (1949). “Lithium chloride as a substitute for sodium chloride in the diet.” J. Amer. tried. Ass., 139, 688–92.Google Scholar
Johansen, K. T., and Ulrich, K. (1969). “Preliminary studies on the possible teratogenic effect of lithium.” Acta psychiat. Scand., Suppl. 207, 91–5.Google Scholar
Kruhøffer, P., Thaysen, J. H., and Thorn, N. A. (1960). “The alkali metals in the organism.” In: The Alkali Metal Ions in Biology. Handbuch der experimentellen Pharmakologie, vol. 13. Springer: Berlin.Google Scholar
Little, B. R., Platman, S. R., and Fieve, R. R. (1968). “The measurement of lithium in biologic samples by atom absorption spectrophotometry.” Clin. Chem., 14, 1211–17.CrossRefGoogle Scholar
Schou, M. (1957). “Biology and pharmacology of the lithium ion.” Pharmacol. Rev., 9, 1758.Google Scholar
Schou, M. (1958). “Lithium studies. 3. Distribution between serum and tissues.” Acta pharmacol. (Kbh.), 15, 115–24.CrossRefGoogle Scholar
Schou, M. (1968). “Lithium in psychiatric therapy and prophylaxis.” J. psychiat. Res., 6, 6795.CrossRefGoogle Scholar
Schou, M., Amdisen, A., Jensen, S. E., and Olsen, T. (1968a). “Occurrence of goitre during lithium treatment.” Brit. med. J., iii, 710–13.Google Scholar
Schou, M., Amdisen, A., Trap-Jensen, J. (1968b). “Lithium poisoning.” Amer. J. Psychiat., 125, 520–7.CrossRefGoogle ScholarPubMed
Schou, M., and Amdisen, A. (1969). “Lithium and foetal abnormalities.” Brit. med. J., i, 316.CrossRefGoogle Scholar
Schou, M., Amdisen, A., and Thomsen, K. (1969). “The effect of lithium on the normal mind.” In: Psychiatria Progrediens. Baudi$sn, P., Peterová, E., and $Snedivec, V. (Editors). Plzen. (In the press.) Google Scholar
Sedvall, G., Jönsson, B., Pettersson, U., and Levin, K. (1968). “Effects of lithium salts on plasma protein bound iodine and uptake of I131 in thyroid gland of man and rat.” Life Sci., 7, 1257–64.CrossRefGoogle Scholar
Thomsen, K., and Schou, M. (1968). “Renal lithium excretion in man.” Amer. J. Physiol., 215, 823–7.CrossRefGoogle Scholar
Trautner, E. M., Pennycuik, P. R., Morris, R. J. H., Gershon, S., and Shankly, K. H. (1958). “The effects of prolonged sub-toxic lithium ingestion on pregnancy in rats.” Aust. J. exp. Biol. med. Sci., 36, 305–22.CrossRefGoogle Scholar
Verbov, J. L., Phillips, J. D., and Fife, D. G. (1965). “A case of lithium intoxication.” Postgrad, med. J., 41, 190–92.CrossRefGoogle Scholar
Wiggers, S. (1968). “Lithiumpåvirkning af glandula thyreoidea?” Ugeskr. Leg., 130, 1523–25.Google Scholar
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