Hostname: page-component-cd9895bd7-gxg78 Total loading time: 0 Render date: 2024-12-28T19:52:27.516Z Has data issue: false hasContentIssue false
  • English
  • Français

Prader-Willi Syndrome and Psychoses

Published online by Cambridge University Press:  02 January 2018

David J. Clarke
David J. Clarke*
Affiliation:
University of Birmingham Department of Psychiatry, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ
Get access Rights & Permissions [Opens in a new window]

Abstract

Prader-Willi syndrome (PWS) is associated with an insatiable appetite and (often) other maladaptive behaviours (self-injury, sleep disorders, insistence on routines, and temper tantrums). Psychoses are not a recognised feature. Most affected people have a chromosome 15 abnormality (deletion, disomy, structural rearrangement, etc.). Three people with PWS who developed psychotic disorders in early adult life are described. The nature of the psychoses and the significance of the association are discussed.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 163 , Issue 5 , November 1993 , pp. 680 - 684
Copyright
Copyright © Royal College of Psychiatrists, 1993 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Clarke, D. J., Waters, J. & Corbett, J. A. (1989) Adults with Prader-Willi syndrome: abnormalities of sleep and behaviour. Journal of the Royal Society of Medicine, 82, 21–24.CrossRefGoogle ScholarPubMed
Cutting, J. C., Clare, A. W. & Mann, A. H. (1978) Cycloid psychosis: an investigation of the diagnostic concept. Psychological Medicine, 3, 637–648.CrossRefGoogle Scholar
Greenswag, L. R. (1987) Adults with Prader-Willi syndrome: a survey of 232 cases. Developmental Medicine and Child Neurology, 29, 145–152.Google Scholar
Gupta, B. K., Fish, D. N. & Yerevanian, B. I. (1987) Carbamazepin for intermittent explosive disorder in a Prader-Willi syndrome patient. Journal of Clinical Psychiatry, 48, 423.Google Scholar
Kollrack, H. W. & Wolff, D. (1966) Paranoid-halluzinatorische Psychose bei Prader-Labhart-Willi-Fanconi syndrome. Acta Paedopsychiatrica, 33, 309–314.Google ScholarPubMed
Leonhard, K. (1961) Cycloid psychoses - endogenous psychoses which are neither schizophrenic nor manic-depressive. Journal of Mental Science, 107, 633–648.CrossRefGoogle ScholarPubMed
Perris, C. (1988) The concept of cycloid psychotic disorder. Psychiatric Developments, 1, 37–56.Google Scholar
Prader, A., Labhart, A. & Willi, H. (1956) Ein Syndrom von Adipositas, Kleinwuchs, Kryptorchismus und Oligophrenie nach myatonieartigem Zustand im Neugeborenalter. Schweizerische Medizinische Wochenschrift, 86, 1260–1261.Google Scholar
Robinson, W. P., Bottani, A., Yagang, X., et al (1991) Molecular cytogenetic, and clinical investigations of Prader-Willi syndrome patients. American Journal of Human Genetics, 49, 12191234.Google Scholar
Whitman, B. Y. & Accardo, P. J. (1989) Prader-Willi syndrome. Journal of the Royal Society of Medicine, 82, 448.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.