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Quantitative Computed Tomography in Elderly Depressed Patients

Published online by Cambridge University Press:  29 January 2018

Robin J. Jacoby ,
Raymond J. Dolan ,
Raymond Levy  and
Robert Baldy
Robin J. Jacoby
Affiliation:
The Middlesex Hospital, Mortimer Street, London W1N 8AA
Raymond J. Dolan
Affiliation:
The Royal Free Hospital, Pond Street, London NW3 2QG
Raymond Levy
Affiliation:
The Maudsley Hospital
Robert Baldy
Affiliation:
The Maudsley Hospital
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Summary

An index of brain tissue density was obtained from the CT scans of 37 elderly depressed patients by measuring Hounsfield Units (HU) in 12 predefined brain areas. Comparisons were made with 23 patients suffering from senile dementia and 36 healthy controls. As a group the depressed patients resembled the dements more than the controls, although analysis of variance indicated differences between all three groups, controls showing the highest HU values and dements the lowest. In the depressed patients ventricular dilatation, which had already been shown to predict increased mortality, was also associated with lower HU levels. The significance of these and other findings is discussed.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 143 , Issue 2 , August 1983 , pp. 124 - 127
Copyright
Copyright © 1983 The Royal College of Psychiatrists 

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References

Bondareff, W., Baldy, R., & Levy, R. (1981) Quantitative computed tomography in senile dementia. Archives of General Psychiatry, 38, 1365–8.CrossRefGoogle ScholarPubMed
Calloway, S. P., Dolan, R. J., Jacoby, R. J. & Levy, R. (1981) ECT and cerebral atrophy: a computed tomographic study. Acta Psychiatrica Scandinavica, 64, 442–5.Google Scholar
Davies, G., Hamilton, S., Hendrickson, D. E., Levy, R. & Post, F. (1978) Psychological test performance and sedation thresholds of elderly dements, depressives and depressives with incipient brain damage. Psychological Medicine, 8, 103–9.Google Scholar
Hemsi, L. K., Whitehead, A. & Post, F. (1968) Cognitive function and cerebral arousal in elderly depressives and dements. Journal of Psychosomatic Research, 12, 145–56.Google Scholar
Hendrickson, E., Levy, R. & Post, F. (1979) Averaged evoked responses in relation to cognitive and affective state of elderly psychiatric patients. British Journal of Psychiatry, 134, 494–501.CrossRefGoogle ScholarPubMed
Jacoby, R. J. (1981) Dementia, depression and the CT scan. Psychological Medicine, 11, 673–6.CrossRefGoogle ScholarPubMed
Jacoby, R. J., Levy, R. & Dawson, J. M. (1980) Computed tomography in the elderly: 1 The normal population. British Journal of Psychiatry, 136, 249–55.Google Scholar
Jacoby, R. J., Levy, R. (1980a) Computed tomography in the elderly: 2 Senile dementia: diagnosis and functional impairment. British Journal of Psychiatry, 136, 256–69.CrossRefGoogle ScholarPubMed
Jacoby, R. J., Levy, R. (1980b) Computed tomography in the elderly: 3 Affective disorder. British Journal of Psychiatry, 136, 270–5.Google ScholarPubMed
Jacoby, R. J. & Bird, J. M. (1981) Computed tomography and the outcome of affective disorder: a follow-up study of elderly patients. British Journal of Psychiatry, 139, 288–92.Google Scholar
Naeser, M. A., Gebhardt, C. & Levine, H. L. (1980) Decreased computerized tomography numbers in patients with presenile dementia: detection in patients with otherwise normal scans. Archives of Neurology, 37, 401–9.CrossRefGoogle ScholarPubMed
Post, F. (1968) The factor of ageing in affective illness. In Recent Developments in Affective Disorders (eds Coppen, A. and Walk, A.). Ashford, Kent: Headley Brothers.Google Scholar
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