Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-27T13:20:57.986Z Has data issue: false hasContentIssue false
  • English
  • Français

Treatment of Depression in Huntington's Disease with Monoamine Oxidase Inhibitors

Published online by Cambridge University Press:  29 January 2018

M. F. Ford
M. F. Ford*
Affiliation:
Glenside Hospital, Fishponds, Bristol (now Senior Registrar, Netherne Hospital, Coulsdon, Surrey CR3 1 YE)
*
∗ Correspondence
Get access Rights & Permissions [Opens in a new window]

Extract

Depression is common in Huntington's disease. It is customary to treat such patients with tricyclic antidepressants, although there is disagreement about their effectiveness. The use of monomine oxidase inhibitors for depression in HD has not previously been reported; three cases are described here. MAOIs appear to be of value in the management of depression in HD.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 149 , Issue 5 , November 1986 , pp. 654 - 656
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bird, E. D. & Iversen, L. L. (1974) Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia. Brain, 97, 457–472.CrossRefGoogle ScholarPubMed
Bolt, J. M. (1970) Huntington's chorea in the west of Scotland. British Journal of Psychiatry. 116, 259–270.CrossRefGoogle ScholarPubMed
Brandon, S. (1982) Monoamine oxidase inhibitors in depression. British Medical Journal. 285, 1594–1595.CrossRefGoogle ScholarPubMed
Caine, E. D., Hunt, R. D. & Weingartner, H. (1978) Huntington's dementia: clinical and neuropsychological features. Archives of General Psychiatry, 35, 377–384.CrossRefGoogle ScholarPubMed
Caine, E. D., Hunt, R. D. & Shoulson, I. (1983) Psychiatric syndromes in Huntington's disease. American Journal of Psychiatry, 140, 728–733.Google ScholarPubMed
Folstein, S., Folstein, M. & McHugh, P. R. (1979) Psychiatric syndromes in Huntington's disease. In Advances in Neurology, vol. 23 (eds T. N. Chase et al). New York: Raven Press.Google Scholar
Folstein, S., Folstein, M. & McHugh, P. R. (1981) Diagnosis and treatment of Huntington's disease. Comprehensive Therapy. 7, 60–66.Google ScholarPubMed
Huntington, G. (1872) On chorea. Medicine & Surgery Reporter, 26, 317–321.Google Scholar
Koehler, K. & Sass, H. (1984) Affective psychopathology in Huntington's disease: the John Hopkins hypothesis and German psychiatry. Psychological Medicine, 14, 733–737.CrossRefGoogle Scholar
Marsden, C. D. (1983) Movement disorders. In Oxford Textbook of Medicine, Vol 2 (eds D. J. Weatherall, J. G. G. Ledingham & B. A. Warrell), Oxford: Oxford University Press.Google Scholar
McHugh, P. R. & Folstein, M. (1975) Psychiatric syndromes of Huntington's chorea: a clinical and phénoménologie study. In Psychiatry Aspects of Neurologic Disease (eds D. F. Benson & D. Blumer). New York: Grune & Stratton.Google Scholar
Shaw, D. M. (1977) The practical management of affective disorders. British Journal of Psychiatry, 130, 432–451.CrossRefGoogle ScholarPubMed
Shoulson, I. (1981) Huntington's disease: functional capacities in patients treated with neuroleptic and antidepressant drugs. Neurology (NY), 31, 1333–1335.CrossRefGoogle ScholarPubMed
Tyrer, P. (1982) Monoamine oxidase inhibitors and amine precursors. In Drugs in Psychiatric Practice (ed. P. Tyrer). Sevenoaks: Butterworths.Google Scholar
Whittier, J. R., Haydn, G. & Crawford, J. (1962) Effect of imipramine on depression and hyperkinesis in Huntington's disease. American Journal of Psychiatry, 118, 79.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.