Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-28T05:29:12.008Z Has data issue: false hasContentIssue false

The use of Sulthiame with Disturbed Mentally Subnormal Patients

Published online by Cambridge University Press:  29 January 2018

W. R. Moffatt
Affiliation:
Eastern Special Care Management Committee, Muckamore Abbey Hospital, Co. Antrim, Northern Ireland
A. R. Siddiqui
Affiliation:
Eastern Special Care Management Committee, Muckamore Abbey Hospital, Co. Antrim, Northern Ireland
D. N. MacKay
Affiliation:
Eastern Special Care Management Committee, Muckamore Abbey Hospital, Co. Antrim, Northern Ireland

Extract

Published reports on sulthiame have been primarily concerned with its effects as an anticonvulsant. Some investigators have also examined behavioural changes brought about by its use. For example, Haran (1962) found that it reduced irritability and violent behaviour, and generally improved the sociability of epileptic patients. Ingram and Ratcliffe (1963) found that the hyperkinetic behaviour of 16 out of the 18 patients in their sample was either ‘abolished’ or improved. Working with a larger group, Liu (1966) noted ‘over-all clinical improvement’ in the behaviour of 32 out of 50 cases. Kneebone (1968) claimed that 12 out of a total of 18 hyperkinetic children had 'significantly improved behaviour’ with sulthiame.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists, 1970 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Davies, T. S., and Leyshon, M. W. (1963). ‘Ospolot in epilepsy.’ Lancet, ii, 939–40.Google Scholar
Garland, H. G., and Sumner, D. W. (1964). ‘Sulthiame in treatment of epilepsy.’ British Medical Journal, 1, 474–76.Google Scholar
Haran, T. (1962). ‘Ospolot: a preliminary communication.’ Irish Journal of Medical Science, Sixth Series, 427–31.CrossRefGoogle Scholar
Hunter, H., and Stephenson, A. M. (1963). ‘Chlorpromazine and trifluoperazine in the treatment of behaviour abnormalities in the severely subnormal child.’ British Journal of Psychiatry, 109, 411–17.Google Scholar
Ingram, T. T. S., and Ratcliffe, S. G. (1963). ‘Clinical trial of Ospolot in epilepsy.’ Developmental Medicine and Child Neurology, 5, 313–16.Google Scholar
Kneebone, G. M. (1968). ‘The use of sulthiame (Ospolot) in the epileptic child with the hyperkinetic syndrome.’ The Medical Journal of Australia, Vol. 2, 1096–7.Google Scholar
Liu, M. G. (1966). ‘Clinical experience with sulthiame (Ospolot).’ British Journal of Psychiatry, 112, 621–8.CrossRefGoogle ScholarPubMed
Siegel, S. (1956). Nonparametric Statistics, McGraw-Hill.Google Scholar
Weir, T. W. H., Kernohan, G. A., and MacKay, D. N. (1968). ‘The use of pericyazine and chlorpromazine with disturbed mentally subnormal patients.’ British Journal of Psychiatry, 114, 111–2.CrossRefGoogle ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.