Copy Number Variation Distribution in Six Monozygotic Twin Pairs Discordant for Schizophrenia

Christina A. Castellani; Zain Awamleh; Melkaye G. Melka; Richard L. O'Reilly; Shiva M. Singh

doi:10.1017/thg.2014.6

Janes, Peter W. Slape, Christopher I. Farnsworth, Rae H. Atapattu, Lakmali Scott, Andrew M. and Vail, Mary E. 2014. EphA3 biology and cancer. Growth Factors, Vol. 32, Issue. 6, p. 176.

Gordon, Hannah Trier Moller, Frederik Andersen, Vibeke and Harbord, Marcus 2015. Heritability in Inflammatory Bowel Disease. Inflammatory Bowel Diseases, p. 1.

Castellani, Christina A Melka, Melkaye G Diehl, Eric J Laufer, Benjamin I O’Reilly, Richard L and Singh, Shiva M 2015. Dna Methylation in Psychosis: Insights Into Etiology and Treatment. Epigenomics, Vol. 7, Issue. 1, p. 67.

Bayer Andersen, Kirsten Leander Johansen, Jens Hentzer, Morten Smith, Garrick Paul and Dietz, Gunnar P. H. 2016. Protection of Primary Dopaminergic Midbrain Neurons by GPR139 Agonists Supports Different Mechanisms of MPP+ and Rotenone Toxicity. Frontiers in Cellular Neuroscience, Vol. 10, Issue. ,

Lyu, Nan Guan, Li-Li Ma, Hong Wang, Xi-Jin Wu, Bao-Ming Shang, Fan-Hong Wang, Dan Wen, Hong and Yu, Xin 2016. Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing. Chinese Medical Journal, Vol. 129, Issue. 6, p. 690.

Peng, Ruan Zhou, Yi Xie, Hong-Ning Zheng, Ju Xie, Ying-Jun and Yang, Jian-Bo 2016. MCDA twins with discordant malformations: submicroscopic chromosomal anomalies detected by chromosomal microarray analysis and clinical outcomes. Prenatal Diagnosis, Vol. 36, Issue. 8, p. 766.

Bustamante, M. Leonor Herrera, Luisa Gaspar, Pablo A. Nieto, Rodrigo Maturana, Alejandro Villar, María José Salinas, Valeria and Silva, Hernán 2017. Shifting the focus toward rare variants in schizophrenia to close the gap from genotype to phenotype. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Vol. 174, Issue. 7, p. 663.

Reble, Emma Castellani, Christina A. Melka, Melkaye G. O’Reilly, Richard and Singh, Shiva M. 2017. VarScan2 analysis of de novo variants in monozygotic twins discordant for schizophrenia. Psychiatric Genetics, Vol. 27, Issue. 2, p. 62.

Castellani, C. A. Melka, M. G. Gui, J. L. Gallo, A. J. O’Reilly, R. L. and Singh, S. M. 2017. Post‐zygotic genomic changes in glutamate and dopamine pathway genes may explain discordance of monozygotic twins for schizophrenia. Clinical and Translational Medicine, Vol. 6, Issue. 1,

Stamouli, Sofia Anderlid, Britt-Marie Willfors, Charlotte Thiruvahindrapuram, Bhooma Wei, John Berggren, Steve Nordgren, Ann Scherer, Stephen W. Lichtenstein, Paul Tammimies, Kristiina and Bölte, Sven 2018. Copy Number Variation Analysis of 100 Twin Pairs Enriched for Neurodevelopmental Disorders. Twin Research and Human Genetics, Vol. 21, Issue. 1, p. 1.

Alavi, Mohaddeseh Sadat Shamsizadeh, Ali Azhdari-Zarmehri, Hassan and Roohbakhsh, Ali 2018. Orphan G protein-coupled receptors: The role in CNS disorders. Biomedicine & Pharmacotherapy, Vol. 98, Issue. , p. 222.

Chen, Y-C Sudre, G Sharp, W Donovan, F Chandrasekharappa, S C Hansen, N Elnitski, L and Shaw, P 2018. Neuroanatomic, epigenetic and genetic differences in monozygotic twins discordant for attention deficit hyperactivity disorder. Molecular Psychiatry, Vol. 23, Issue. 3, p. 683.

Wang, Shenjie Wang, Jiayin Xiao, Xiao Zhang, Xuanping Wang, Xuwen Zhu, Xiaoyan and Lai, Xin 2019. GSDcreator: An Efficient and Comprehensive Simulator for Genarating NGS Data with Population Genetic Information. p. 1868.

Umstad, Mark P. Calais-Ferreira, Lucas Scurrah, Katrina J. Hall, Judith G. and Craig, Jeffrey M. 2019. Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics. p. 387.

Alblooshi, Hiba Al Safar, Habiba El Kashef, Ahmed Al Ghaferi, Hamad Shawky, Mansour Hulse, Gary K. and Tay, Guan K. 2020. Stratified analyses of genome wide association study data reveal haplotypes for a candidate gene on chromosome 2 (KIAA1211L) is associated with opioid use in patients of Arabian descent. BMC Psychiatry, Vol. 20, Issue. 1,

Imamura, Akira Morimoto, Yoshiro Ono, Shinji Kurotaki, Naohiro Kanegae, Shinji Yamamoto, Naoki Kinoshita, Hirohisa Tsujita, Takahiro Okazaki, Yuji and Ozawa, Hiroki 2020. Genetic and environmental factors of schizophrenia and autism spectrum disorder: insights from twin studies. Journal of Neural Transmission, Vol. 127, Issue. 11, p. 1501.

Vedel, Line Nøhr, Anne Cathrine Gloriam, David E. and Bräuner‐Osborne, Hans 2020. Pharmacology and function of the orphan GPR139 G protein‐coupled receptor. Basic & Clinical Pharmacology & Toxicology, Vol. 126, Issue. S6, p. 35.

Falker-Gieske, Clemens Iffland, Hanna Preuß, Siegfried Bessei, Werner Drögemüller, Cord Bennewitz, Jörn and Tetens, Jens 2020. Meta-analyses of genome wide association studies in lines of laying hens divergently selected for feather pecking using imputed sequence level genotypes. BMC Genetics, Vol. 21, Issue. 1,

Roy, Nisa Ogawa, Satoshi Maniam, Roshan and Parhar, Ishwar 2021. Habenula GPR139 is associated with fear learning in the zebrafish. Scientific Reports, Vol. 11, Issue. 1,

Reichard, Holly A. Schiffer, Hans H. Monenschein, Holger Atienza, Josephine M. Corbett, Gerard Skaggs, Alton W. Collia, Deanna R. Ray, William J. Serrats, Jordi Bliesath, Joshua Kaushal, Nidhi Lam, Betty P. Amador-Arjona, Alejandro Rahbaek, Lisa McConn, Donavon J. Mulligan, Victoria J. Brice, Nicola Gaskin, Philip L. R. Cilia, Jackie and Hitchcock, Stephen 2021. Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia. Journal of Medicinal Chemistry, Vol. 64, Issue. 15, p. 11527.

Save article to Kindle

Save article to Dropbox

Save article to Google Drive

Reply to: Submit a response

Your details

You have entered the maximum number of contributors

Conflicting interests