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A Gerontological Cohort Study of Aged Twins: The Osaka University Aged Twin Registry

Published online by Cambridge University Press:  21 February 2012

Kazuo Hayakawa ,
Tadahiko Shimizu ,
Kenji Kato ,
Miyuki Onoi  and
Yoko Kobayashi
Kazuo Hayakawa*
Affiliation:
School of Health Science, Faculty of Medicine, Osaka University, Osaka, Japan. hayakawa@sahs.med.osaka-u.ac.jp
Tadahiko Shimizu
Affiliation:
Department of Public Health, Faculty of Medicine, Kinki University, Osaka, Japan.
Kenji Kato
Affiliation:
School of Health Science, Faculty of Medicine, Osaka University, Osaka, Japan.
Miyuki Onoi
Affiliation:
School of Health Science, Faculty of Medicine, Osaka University, Osaka, Japan.
Yoko Kobayashi
Affiliation:
School of Health Science, Faculty of Medicine, Osaka University, Osaka, Japan.
*
*Address for correspondence: Kazuo Hayakawa, School of Health Science, Faculty of Medicine, Osaka University. 1-7 Yamadaoka, Suita-city, Osaka, 565-0871, Japan.

Abstract

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We describe subject recruitment and research results from the Osaka University Aged Twin Registry (OUATR). The research focus of OUATR is the genetic and environmental contributions to physical-cognitive-mental aging which we examined in Japanese twins in later adulthood. Within this large-scale registry (12,000 pairs) of oriental twins born between 1900 and 1935, approximately 10% of participants are MZ twins reared apart from early childhood. Two hundred and fifty pairs have had comprehensive medical examinations, including various blood chemical panels, lymphocyte subtests, WAIS (Wechsler Adult Intelligence Scale), and urine analysis. The future foci of this study are primarily on longevity, decline of cognitive functions with aging, bio-physiological functions, lifestyle and behavior genetics, and psycho-spiritual functions.

Type
Articles/Japan
Information
Twin Research and Human Genetics , Volume 5 , Issue 5 , 01 October 2002 , pp. 387 - 388
Copyright
Copyright © Cambridge University Press 2002