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Multi-Fetal Pregnancy Reduction Does Not Influence Perinatal Results in Twin Pregnancies

Published online by Cambridge University Press:  21 February 2012

Simona Jirsova ,
Tonko Mardesic ,
Pavel Muller ,
Renata Huttelova ,
Jana Zvarova  and
Milan Jirkovsky
Simona Jirsova
Affiliation:
Institut Pronatal, Na Dlouhe mezi 4/12, 147 00, Prague 4, Czech Republic.
Tonko Mardesic*
Affiliation:
Institut Pronatal, Na Dlouhe mezi 4/12, 147 00, Prague 4, Czech Republic. pronatal@mbox.vol.cz
Pavel Muller
Affiliation:
Institut Pronatal, Na Dlouhe mezi 4/12, 147 00, Prague 4, Czech Republic.
Renata Huttelova
Affiliation:
Institut Pronatal, Na Dlouhe mezi 4/12, 147 00, Prague 4, Czech Republic.
Jana Zvarova
Affiliation:
EuroMISE Statistical Center of Charles University and Academy of Sciences, Pod vodarenskou vezi 2, 182 07, Prague 8, Czech Republic.
Milan Jirkovsky
Affiliation:
EuroMISE Statistical Center of Charles University and Academy of Sciences, Pod vodarenskou vezi 2, 182 07, Prague 8, Czech Republic.
*
*Address for correspondence: T Mardesic, Institut Pronatal, Na Dlouhe mezi 4/12, 147 00, Prague 4, Czech Republic.

Abstract

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The objective of this study was to compare perinatal results in multifetal pregnancies where the reduction to twins was performed with non-reduced twin pregnancies. Perinatal results in 99 sets of twins after transabdominal multifetal pregnancy reduction of triple and higher-order multiple pregnancies performed in a single center were compared with a control group consisting of 151 twin pregnancies conceived in the same time period after infertility treatment, which were not a result of reduction. The main outcome measures were length of pregnancies, weight of the newborns, percentage of miscarriages and the mode of the delivery were analyzed. No significant difference could be found at a 5% level of significance regarding the average duration of pregnancy or average weight of the twins. Fisher test on 5% significance level did not ascertain any significant difference in the probability of miscarriage between the group with reduction (5.26%) and the group without reduction (12.84%). At a 5% level of statistical significance, no significant difference in probability of perinatal death of the fetus or delivery of a stillborn fetus was found. The percentage of cesarean sections did not differ significantly in both groups. The analysis of both groups demonstrated that reduction of multifetal pregnancies to twins may not influence perinatal results in comparison to twin pregnancies where reduction was not performed.

Type
Articles
Information
Twin Research and Human Genetics , Volume 4 , Issue 6 , 01 December 2001 , pp. 422 - 425
Copyright
Copyright © Cambridge University Press 2001