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The Swedish Twin Registry in the Third Millennium

Published online by Cambridge University Press:  21 February 2012

Nancy L. Pedersen ,
Paul Lichtenstein  and
Pia Svedberg
Nancy L. Pedersen*
Affiliation:
Department of Medical Epidemiology, Karolinska Institutet, Sweden; Department of Psychology, University of Southern California, USANancy.Pedersen@mep.ki.se
Paul Lichtenstein
Affiliation:
Department of Medical Epidemiology, Karolinska Institutet, Sweden
Pia Svedberg
Affiliation:
Department of Medical Epidemiology, Karolinska Institutet, Sweden
*
*Address for correspondence: Nancy L. Pedersen, Department of Medical Epidemiology, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden.

Abstract

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Since the Swedish Twin Registry was first established in the late 1950s to study the importance of smoking and alcohol consumption on cancer and cardiovascular diseases, it has been expanded and updated on several occasions. The focus has similarly broadened to most common complex diseases. The content of the database is described, ongoing projects based on the registry are summarized, and we review some of the principal findings on aging, cancer and cardiovascular disease that have come from the registry. Ongoing efforts and future plans for the STR are discussed. Among others, we plan blood collection and genotyping to study the genetic bases of complex diseases, a first contact ever with the cohorts born after 1958, and in-depth studies of selected diseases, such as Parkinson’s disease and chronic fatigue syndrome.

Type
Articles/Sweden
Information
Twin Research and Human Genetics , Volume 5 , Issue 5 , 01 October 2002 , pp. 427 - 432
Copyright
Copyright © Cambridge University Press 2002