Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-26T08:18:43.407Z Has data issue: false hasContentIssue false
  • English
  • Français

A double-labeling investigation of the pretectal visuo-vestibular pathways

Published online by Cambridge University Press:  02 June 2009

M. Magnin ,
H. Kennedy  and
K. P. Hoffmann
M. Magnin
Affiliation:
Laboratoire de Neuropsychologie Expérimentale, I.N.S.E.R.M. U.94, Bron, France
H. Kennedy
Affiliation:
Laboratoire de Neuropsychologie Expérimentale, I.N.S.E.R.M. U.94, Bron, France
K. P. Hoffmann
Affiliation:
Lehrstuhl für Allgemeine Zoologie and Neurobiologie, Ruhr-Universität Bochum, Federal Republic of Germany
Get access Rights & Permissions [Opens in a new window]

Abstract

The projections of the nucleus of the optic tract were studied in the cat by simultaneous use of two distinct retrograde tracers (Fast Blue and Diamidino Yellow) injected in the inferior olive and the prepositus hypoglossi nucleus. Following injections of diamidino yellow in one structure and fast blue in the other, a significant number of retrogradely labeled neurons projecting to either target were observed dispersed in the nucleus of the optic tract. Three populations of labeled cells were found: one which projected to the inferior olive, a second to the nucleus prepositus hypoglossi, and a third which projected by means of a bifurcating axon to both of these structures. Quantification of these results reveals that 72% of the total number of labeled neurons are labeled by the IO injection, the remaining cells being labeled by the NPH injection. Double-labeled neurons represent more than 7% of the total number of the labeled cells. Tentative inferences as to the electrophysiological properties of the nucleus of the optic tract are discussed in the context of the optokinetic system.

Keywords

PretectumInferior olivePrepositus hypoglossi nucleusCat
Type
Research Articles
Information
Visual Neuroscience , Volume 3 , Issue 1 , July 1989 , pp. 53 - 58
Copyright
Copyright © Cambridge University Press 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Balaban, C. (1983). A projection from nucleus reticularis tegmenti pontis of Bechterew to the medial vestibular nucleus in rabbits. Experimental Brain Research 51, 304–309.CrossRefGoogle Scholar
Barmack, N. & Pettorossi, V. (1985). Effects of unilateral lesions of the flocculus on optokinetic and vestibuloocular reflexes of the rabbit. Journal of Neurophysiology 53, 481–496.CrossRefGoogle ScholarPubMed
Berman, A. (1968). The Brain Stem of the Cat. A Cytoarchilectonic Atlas with Stereotaxic Coordinates. Madison: University of Wisconsin Press.Google Scholar
Brodal, A. (1940). Modification of Gudden method for study of cerebral localization. Archives of Neurology and Psychiatry 43, 46–58.Google Scholar
Bullier, J., Kennedy, H. & Salinger, W. (1984). Bifurcation of subcortical afférents to the visual areas 17, 18, and 19 in the cat cortex. Journal of Comparative Neurology 228, 309–328.Google Scholar
Cazin, L., Magnin, M. & Lannou, J. (1982). Non-cerebellar visual afferents to the vestibular nuclei involving the prepositus hypoglossal complex: an autoradiographic study in the rat. Experimental Brain Research 48, 309–313.CrossRefGoogle Scholar
Ferrer, J.M.R., Price, D.J. & Blakemore, C. (1988). The organization of cortico-cortical projections from area 17 to area 18 of the cat's visual cortex. Proceedings of the Royal Society B (London) 233, 77–98.Google Scholar
Giolli, R., Blanks, R. & Torigoe, Y. (1984). Pretectal and brain stem projections of the medial terminal nucleus of the accessory optic system of the rabbit and rat as studied by anterograde and retrograde neuronal tracing methods. Journal of Comparative Neurology 227, 228–251.Google Scholar
Godaux, E. & Vanderkelen, B. (1984). Vestibulo-ocular reflex, optokinetic response, and their interactions in the cerebellectomized cat. Journal of Physiology (London) 346, 155–170.CrossRefGoogle ScholarPubMed
Grasse, K. & Cynader, M. (1984). Electrophysiology of lateral and dorsal terminal nuclei of the cat accessory optic system. Journal of Neurophysiology 51, 276–293.CrossRefGoogle ScholarPubMed
Hoffmann, K.P., Behrend, K. & Schoppmann, A. (1976). A direct visual pathway from the nucleus of the optic tract to the inferior olive in the cat. Brain Research 115, 150–153.Google Scholar
Hoffmann, K. & Schoppmann, A. (1981). A quantitative analysis of the direction-specific response of neurons in the cat's nucleus of the optic tract. Experimental Brain Research 42, 146–157.CrossRefGoogle ScholarPubMed
Holstege, G. & Collewijn, H. (1982). The efferent connections of the nucleus of the optic tract and the superior colliculus in the rabbit. Journal of Comparative Neurology 209, 139–175.CrossRefGoogle ScholarPubMed
Ito, M. (1984). Multiple ocular reflexes. In The Cerebellum and Neural Control, ed. Ito, M. pp. 374–388. New York: Raven Press.Google Scholar
Kanaseki, T. & Sprague, J. (1974). Anatomical organization of pretectal nuclei and tectal laminae in the cat. Journal of Comparative Neurology 158, 319–338.CrossRefGoogle ScholarPubMed
Kawamura, K. & Hashikawa, T. (1979). Olivocerebellar projections in the cat studied by means of anterograde axonal transport of labeled amino acids as tracers. Neuroscience 4, 1615–1633.CrossRefGoogle ScholarPubMed
Kawamura, K. & Onodera, S. (1984). Olivary projections from the pretectal region in the cat studied with horseradish peroxidase and tritiated amino acids axonal transport. Archives Italiennes de Biologie 122, 155–168.Google ScholarPubMed
Keller, E. & Precht, W. (1979). Visual-vestibular responses in vestibular nuclear neurons in the intact and cerebellectomized alert cat. Neuroscience 4, 1599–1613.CrossRefGoogle ScholarPubMed
Kennedy, H. & Bullier, J. (1985). A double-labeling investigation of the afferent connectivity to cortical areas V1 and V2 of the macaque monkey. Journal of Neuroscience 5, 2815–2830.CrossRefGoogle ScholarPubMed
Kuypers, H.G., Bentivoglio, M., Catsman-Berrevoets, C.E. & Bharos, A.T. (1980). Double retrograde neuronal labeling through divergent axon collaterals, using two fluorescent tracers with the same excitation wavelength which label different features of the cell. Experimental Brain Research 40, 383–392.Google Scholar
Langer, T., Fuchs, A., Scudder, C. & Chubb, M. (1985). Afferents to the flocculus of the cerebellum in the rhesus macaque as revealed by retrograde transport of horseradish peroxidase. Journal of Comparative Neurology 235, 1–25.CrossRefGoogle Scholar
Maekawa, K. & Simpson, J.I. (1973). Climbing fiber responses evoked in vestibulocerebellum of rabbit from visual system. Journal of Neurophysiology 36, 649–666.CrossRefGoogle ScholarPubMed
Magnin, M., Courjon, J. & Flandrin, J. (1983). Possible visual pathways to the cat vestibular nuclei involving the nucleus prepositus hypoglossi. Experimental Brain Research 51, 298–303.CrossRefGoogle Scholar
McCrea, R. & Baker, R. (1985). Anatomical connections of the nucleus prepositus of the cat. Journal of Comparative Neurology 237, 377–407.Google Scholar
Mizuno, N., Mochizuki, K., Akimoto, C. & Matsushima, R. (1973). Pretectal projections to the inferior olive in the rabbit. Experimental Neurology 39, 498–506.CrossRefGoogle Scholar
Precht, W., Cazin, L., Blanks, R. & Lannou, J. (1982). Anatomy and physiology of the optokinetic pathways to the vestibular nuclei in the rat. In Physiological and Pathological Aspects of Eye Movements, ed. Roucoux, A. & Crommelinck, M., pp. 153–172. The Hague: D.W. Junk.CrossRefGoogle Scholar
Saint-Cyr, J. & Courville, J. (1980). Projections from motor cortex, midbrain, and vestibular nuclei to the inferior olive in the cat: anatomical organization and functional correlates. In The Inferior Olivary Nucleus: Anatomy and Physiology, ed. Courville, J., De Montigny, C. & Lamarre, Y., pp. 97–124. New York: Raven Press.Google Scholar
Simpson, J., Soodak, R. & Hess, R. (1979). The accessory optic system and its relation to the vestibulocerebellum. In Reflex Control of Posture and Movement, ed. Granit, R. & Pompeiano, O., pp. 715–724. Progress in Brain Research, Vol. 50, Amsterdam: Elsevier.CrossRefGoogle Scholar
Weber, J.T. (1985). Pretectal complex and accessory optic system of primates. Brain Behaviour and Evolution 26, 117–140.CrossRefGoogle ScholarPubMed