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Effect of strabismus on the development of vernier acuity and grating acuity in monkeys

Published online by Cambridge University Press:  02 June 2009

Lynne Kiorpes
Lynne Kiorpes
Affiliation:
Center for Neural Science and Department of Psychology, New York University, New York
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Abstract

The effect of experimental strabismus on the development of vernier acuity and grating acuity was studied in Macaca nemestrina monkeys. Six monkeys were studied longitudinally beginning near 10 days after birth. Four of the six monkeys developed amblyopia. As is true for human strabismic amblyopes, the deficit in vernier acuity was larger than the deficit in grating acuity in the amblyopic monkeys. The developmental data reveal that this differential disruption of vernier acuity can be understood as a result of a slowed developmental process associated with amblyopia.

Keywords

StrabismusVisual developmentVernier acuityGrating acuityMacaque monkeyAmblyopia
Type
Research Articles
Information
Visual Neuroscience , Volume 9 , Issue 3-4 , October 1992 , pp. 253 - 259
Copyright
Copyright © Cambridge University Press 1992

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References

Banks, M.S. & Bennett, P.J. (1988). Optical and photoreceptor immaturities limit the spatial and chromatic vision of human neonates. Journal of the Optical Society of America A 5(12), 2059–2079.CrossRefGoogle ScholarPubMed
Bedell, H.E. & Flom, M.C. (1981). Monocular spatial distortion in strabismic amblyopia. Investigative Ophthalmology and Visual Science 20(2), 263–268.Google ScholarPubMed
Bedell, H.E., Flom, M.C. & Barbeito, R. (1985). Spatial aberrations and acuity in strabismus and amblyopia.Investigative Ophthalmology and Visual Science 26(7), 909–916.Google Scholar
Blakemore, C. & Vital-Durand, F. (1986a). Organization and postnatal development of the monkey's lateral geniculate nucleus. Journal of Physiology 380, 453–491.CrossRefGoogle ScholarPubMed
Blakemore, C. & Vital-Durand, F. (1986b). Effects of visual deprivation on the development of the monkey's lateral geniculate nucleus. Journal of Physiology 380, 493–511.CrossRefGoogle ScholarPubMed
Boothe, R.G., Dobson, M.V. & Teller, D.Y. (1985). Postnatal development of vision in human and nonhuman primates. Annual Review of Neuroscience 8, 495–545.CrossRefGoogle ScholarPubMed
Brown, A.M., Dobson, M.V. & Maier, J. (1987). Visual acuity of human infants at scotopic, mesopic and photopic luminances. Vision Research 27(10), 1845–1858.CrossRefGoogle ScholarPubMed
Egoers, H.M., Gizzi, M.S. & Movshon, J.A. (1984). Spatial properties of striate cortical neurons in esotropic macaques. Investigative Ophthalmology and Visual Science 25(3), 278.Google Scholar
Fahle, M. & Schmid, M. (1988). Naso-temporal asymmetry of visual perception and of the visual cortex. Vision Research 28(2), 293–300.CrossRefGoogle ScholarPubMed
Fronius, M. & Sireteanu, R. (1989). Monocular geometry is selectively distorted in the central visual field of strabismic amblyopes. Investigative Ophthalmology and Visual Science 30(9), 2034–2044.Google ScholarPubMed
Harwerth, R.S., Smith, E.L., Boltz, R.L., Crawford, M.L.J. & Vonnoorden, G.K. (1983). Behavioral studies on the effect of abnormal early visual experience in monkeys: Spatial modulation sensitivity. Vision Research 23, 1501–1510.CrossRefGoogle ScholarPubMed
Hendrickson, A.E., Movshon, J.A., Eggers, H.M., Gizzi, M.S., Boothe, R.G. & Kiorpes, L. (1987). Effects of early unilateral blur on the macaque's visual system. II. Anatomical observations. Journal of Neuroscience 7(5), 1327–1339.CrossRefGoogle ScholarPubMed
Hess, R.F., Campbell, F.W. & Greenhalgh, T. (1978). On the nature of the neural abnormality in human amblyopia; neural aberrations and neural sensitivity loss. Pflügers Archiv 377, 201–207.CrossRefGoogle ScholarPubMed
Jacobs, D.S. & Blakemore, C. (1988). Factors limiting the postnatal development of visual acuity in the monkey. Vision Research 28(8), 947–958.CrossRefGoogle ScholarPubMed
Kiorpes, L. (1989). The development of spatial resolution and contrast sensitivity in naturally strabismic monkeys. Clinical Vision Sciences 4(4), 279–293.Google Scholar
Kiorpes, L. (1992). Development of vernier acuity and grating acuity in normally reared monkeys. Visual Neuroscience 9, 243–251.CrossRefGoogle ScholarPubMed
Kiorpes, L., Carlson, M.R. & Alfi, D. (1989). Development of visual acuity in experimentally strabismic monkeys. Clinical Vision Sciences 4(2), 95–106.Google Scholar
Kiorpes, L. & Boothe, R.G. (1984). Accommodative range in amblyopic monkeys (Macaca nemestrina). Vision Research 24, 1829–1834.CrossRefGoogle ScholarPubMed
Kiorpes, L. & Movshon, J.A. (1989). Differential development of two visual functions in primates. Proceedings of the National Academy of Sciences of the U.S.A. 86, 8998–9001.CrossRefGoogle ScholarPubMed
Levi, D.M. & Klein, S.A. (1982). Differences in vernier discrimination for gratings between strabismic and anisometropic amblyopes. Investigative Ophthalmology and Visual Science 23, 398–407.Google ScholarPubMed
Levi, D.M. & Klein, S.A. (1983). Spatial localization in normal and amblyopic vision. Vision Research 23(10), 1005–1017.CrossRefGoogle ScholarPubMed
Levi, D.M. & Klein, S.A. (1985). Vernier acuity, crowding and amblyopia. Vision Research 25(7), 979–991.CrossRefGoogle ScholarPubMed
Levi, D.M., Klein, S.A. & Aitsebaomo, A.P. (1985). Vernier acuity, crowding and cortical magnification. Vision Research 25(7), 963–977.CrossRefGoogle Scholar
Levitt, J.B., Movshon, J.A., Sherman, S.M. & Spear, P.D. (1989). Effects of monocular deprivation on macaque LGN. Investigative Ophthalmology and Visual Science 30(3), 296.Google Scholar
Mood, A.A., Graybill, F.A. & Boes, D.C. (1974). Introduction to the Theory of Statistics, 3rd ed., pp. 440–442. New York: McGraw-Hill.Google Scholar
Movshon, J.A. & Kiorpes, L. (1992). Biological limits on visual development in primates. In Infant Vision: Basic and Clinical Reserach, ed. Simons, K., New York: Oxford University Press (in press).Google Scholar
Movshon, J.A., Eggers, H.M., Gizzi, M.S., Hendrickson, A.E., Kiorpes, L. & Boothe, R.G. (1987). Effects of early unilateral blur on the macaque's visual system. III. Physiological observations. Journal of Neuroscience 7(5), 1340–1351.CrossRefGoogle Scholar
Parker, A. & Hawken, M.J. (1985). Capabilities of monkey cortical cells in spatial-resolution tasks. Journal of the Optical Society of America A 2(7), 1101–1114.CrossRefGoogle ScholarPubMed
Scott, A.B. (1987). Antitoxin prevents botulinum side-effects. Investigative Ophthalmology and Visual Science 28(3) 153.Google Scholar
Scott, A.B., Rosenbaum, A. & Collins, C. (1973). Pharmacologic weakening of extraocular muscles. Investigative Ophthalmology and Visual Science 12, 924–927.Google ScholarPubMed
Smith, E.L. & Harwerth, R.S. (1984). Behavioral measurements of accommodative amplitude in Rhesus monkeys. Vision Research 24(12), 1821–1827.CrossRefGoogle ScholarPubMed
Von Noorden, G.K. (1980). Burian and von Noordens Binocular Vision and Ocular Motility: Theory and Management of Strabismus. St. Louis, MO: C.V. Mosby, Co.Google Scholar
Von Noorden, G.K. & Dowling, J.E. (1970). Experimental amblyopia in monkeys. II. Behavioral studies of strabismic amblyopia. Archives of Ophthalmology 84, 206–214.CrossRefGoogle ScholarPubMed
Wassle, H., Grunert, U., Rohrenbeck, J. & Boycott, B.B. (1990). Retinal ganglion cell density and cortical magnification factor in the primate. Vision Research 30(11), 1897–1911.CrossRefGoogle ScholarPubMed
Westheimer, G. (1982). The spatial grain of the perifoveal visual field. Vision Research 22, 157–162.CrossRefGoogle ScholarPubMed
Wilson, H.R. (1988). Development of spatiotemporal mechanisms in infant vision. Vision Research 28, 611–628.CrossRefGoogle Scholar
Young, F.A. (1964). The distribution of refractive errors in monkeys. Experimental Eye Research 3, 230–246.CrossRefGoogle ScholarPubMed