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The effects of lateral geniculate nucleus, area V4, and middle temporal (MT) lesions on visually guided eye movements

Published online by Cambridge University Press:  02 June 2009

Peter H. Schiller  and
Kyoungmin Lee
Peter H. Schiller
Affiliation:
Massachusetts Institute of Technology, Cambridge, Massachusetts
Kyoungmin Lee
Affiliation:
Massachusetts Institute of Technology, Cambridge, Massachusetts
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Abstract

Visually guided saccadic eye movements to singly presented stationary targets form a bimodal distribution. After superior colliculus lesions, the so called “express saccades” that form the first mode of the distribution are no longer obtained. The aim of this study was to determine what role several other neural systems play in the generation of express and regular saccades, with the latter being those that form the second mode in the bimodal distribution. Lesions were made in the parvocellular and magnocellular portions of the lateral geniculate nucleus to disrupt either the midget system or the parasol system that originates in the retina and areas V4 and MT. The effects of the lesions were examined on the accuracy and latency of saccadic eye movements made to stationary and to moving visual targets. Following magnocellular and MT lesions deficits were observed in smooth pursuit and in the amplitude of saccades made to moving targets. However, none of the lesions produced significant changes in the bimodal distribution of saccadic latencies to stationary targets. The results suggest that express saccades and regular saccades are not selectively mediated by either the midget or the parasol systems or by areas V4 and MT. Neither are the frontal eye fields involved as had previously been shown. We suggest that the superior colliculus plays a central role in producing both express and regular saccades by virtue of highly convergent input from numerous cortical structures.

Keywords

Visual systemExtrastriate cortexEye movements
Type
Research Articles
Information
Visual Neuroscience , Volume 11 , Issue 2 , March 1994 , pp. 229 - 241
Copyright
Copyright © Cambridge University Press 1994

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