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Seeing beyond the midline: The role of the contralateral isthmotectal projection in the leopard frog

Published online by Cambridge University Press:  02 June 2009

Brett C. Weber ,
Robert F. Waldeck  and
Edward R. Gruberg
Brett C. Weber
Affiliation:
Biology Department, Temple University, Philadelphia
Robert F. Waldeck
Affiliation:
Biology Department, Temple University, Philadelphia
Edward R. Gruberg
Affiliation:
Biology Department, Temple University, Philadelphia
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Abstract

The ground level visual field of each eye of the leopard frog includes the entire ipsilateral 180-deg field and approximately 60 deg into the frontal contralateral field. When one eye is covered with an opaque patch, a frog responds to prey stimuli over the entire field of the other eye. Nevertheless, when one optic nerve is cut, the animal responds to prey in the ipsilateral hemifield of the connected eye, but only responds as far as about 30 deg past the frontal midline. If one optic tract is cut, the animal does not respond to prey past the frontal midline. We hypothesized that the responses past the frontal midline might be mediated by input from contralaterally projecting isthmotectal fibers. These fibers originate in the nucleus isthmi, a posterior midbrain structure. We found that when we placed an opaque patch over one eye and either ablated the ipsilateral nucleus isthmi, or cut crossing isthmotectal fibers in the optic chiasm, or blocked input to nucleus isthmi by ablating the ipsilateral tectal lobe, animals did not respond to prey stimuli past the frontal midline. We found that when we placed an opaque patch over one eye and cut crossing optic fibers in the anterior part of the optic chiasm (sparing crossing isthmotectal fibers), animals responded to prey stimuli in the nasal half of the seeing eye's contralateral frontal field. Our results suggest that contralaterally projecting isthmotectal fibers enable the frog to respond to stimuli past the frontal midline. We suggest a one-dimensional model of how nucleus isthmi influences tectal function.

Keywords

Nucleus isthmiPrey catchingOptic tectumOptic nerveOptic tract
Type
Research Articles
Information
Visual Neuroscience , Volume 13 , Issue 3 , May 1996 , pp. 467 - 476
Copyright
Copyright © Cambridge University Press 1996

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References

Caine, H.S. & Gruberg, E.R. (1985). Ablation of nucleus isthmi leads to loss of specific visually elicited behaviors in the frog Rana pipiens. Neuroscience Letters 54, 307–312.CrossRefGoogle ScholarPubMed
Comer, C. & Grobstein, P. (1978). Prey acquisition in atectal frogs. Brain Research 153, 217–221.CrossRefGoogle ScholarPubMed
Desan, P.H., Gruberg, E.R., Grewell, K.M. & Eckenstein, F. (1987). Cholinergic innervation of the optic tectum in the frog Rana pipiens. Brain Research 413, 344–349.CrossRefGoogle ScholarPubMed
Fite, K.V. (1973). The visual fields of the frog and toad: A comparative study. Journal of Behavioral Biology 9, 707–718.CrossRefGoogle ScholarPubMed
Glasser, S. & Ingle, D. (1978). The nucleus isthmus as a relay station in the ipsilateral visual projection to the frog's optic tectum. Brain Research 159, 214–218.CrossRefGoogle Scholar
Graybiel, A.M. (1978). A satellite system of the superior colliculus: The parabigeminal nucleus and its projections to the superficial collicular layers. Brain Research 145, 365–374.CrossRefGoogle Scholar
Grobstein, P. & Comer, C. (1983). The nucleus isthmi as an intertectal relay for the ipsilateral oculotectal projection in the frog, Rana pipiens. Journal of Comparative Neurology 217, 54–74.CrossRefGoogle ScholarPubMed
Grobstein, P., Comer, C., Hollyday, M. & Archer, S.M. (1978). A crossed isthmo-tectal projection in Rana pipiens and its involvement in the ipsilateral visuotectal projection. Brain Research 156, 117–123.CrossRefGoogle ScholarPubMed
Grobstein, P., Comer, C. & Kostyk, S. (1980). The potential binocular field and its tectal representation in Rana pipiens. Journal of Comparative Neurology 190, 175–185.CrossRefGoogle ScholarPubMed
Gruberg, E.R. (1989). Nucleus isthmi and optic tectum in frogs. In Visuomotor Coordination, ed. Ewert, J.-P. & Arbib, M.A., pp. 341–356. New York: Plenum Press.CrossRefGoogle Scholar
Gruberg, E.R., Hughes, T.E. & Karten, H.J. (1994). Synaplic interrelationships between the optic tectum and the ipsilateral nucleus isthmi in Rana pipiens. Journal of Comparative Neurology 339, 353–364.CrossRefGoogle ScholarPubMed
Gruberg, E.R. & Lettvin, J.Y. (1980). Anatomy and physiology of a binocular system in the frog Rana pipiens. Brain Research 192, 313–325.CrossRefGoogle ScholarPubMed
Gruberg, E.R. & Udin, S.B. (1978). Topographic projections between the nucleus isthmi and the tectum of the frog Rana pipiens. Journal of Comparative Neurology 179, 487–500.CrossRefGoogle ScholarPubMed
Gruberg, E.R., Wallace, M.T. & Waldeck, R.F. (1989). Relationship between isthmotectal fibers and other tectopetal systems in the leopard frog. Journal of Comparative Neurology 288, 39–50.CrossRefGoogle ScholarPubMed
Gruberg, E.R., Wallace, M.T., Caine, H.S. & Mote, M.I. (1991). Behavioral and physiological consequences of unilateral ablation of the nucleus isthmi in the leopard frog. Brain, Behavior, and Evolution 37, 92–103.Google ScholarPubMed
Ingle, D. (1973). Two visual systems in the frog. Science 81, 1053–1055.CrossRefGoogle Scholar
Khalil, S.H. & Lázár, G. (1977). Nucleus isthmi of the frog: Structure and tecto-isthmic projection. Acta Morphologica Academiae Scientiarum Hungaricae 25, 51–59.Google ScholarPubMed
King, W.M. (1990). Nicotinic depolarization of optic nerve terminals augments synaptic transmission. Brain Research 527, 150–154.CrossRefGoogle ScholarPubMed
Koch, C. & Ullman, S. (1985). Shifts in selective visual attention: Towards the underlying neural circuitry. Human Neurobiology 4, 219–227.Google ScholarPubMed
Kostyk, S.K. & Grobstein, P. (1987). Neuronal organization underlying visually elicited prey orienting in the frog–III. Evidence for the existence of an uncrossed descending tectofugal pathway. Neuroscience 21, 83–96.CrossRefGoogle ScholarPubMed
Newman, E.A., Gruberg, E.R. & Hartline, P.H. (1980). The infrared trigemino-tectal pathway in the rattlesnake and in the python. Journal of Comparative Neurology 191, 465–477.CrossRefGoogle ScholarPubMed
Sargent, P.B., Pike, S.H., Nadel, D.B. & Lindstrom, J.M. (1989). Nicotinic acetylcholine receptor-like molecules in the retina, retinotectal pathway and optic tectum of the frog. Journal of Neuroscience 9, 565–573.CrossRefGoogle ScholarPubMed
Sherk, H. (1979). Connections and visual-field mapping in cat's tectoparabigeminal circuit. Journal of Neurophysiology 42, 1656–1668.CrossRefGoogle ScholarPubMed
Snedecor, G.W. & Cochran, W.G. (1980). Statistical Methods, 7th Edition, pp. 144–145. Ames, Iowa: Iowa State University Press.Google Scholar
Tóth, P., Lázár, G., Wang, S.-H., Li, T.-B., Xu, J., Pál, E. & Straznicky, C. (1994). The contralaterally projecting neurons of the isthmic nucleus in five anuran species: A retrograde tracing study with HRP and cobalt. Journal of Comparative Neurology 346, 306–320.CrossRefGoogle ScholarPubMed
Udin, S.B., Fisher, M.D. & Norden, J.J. (1990). Ultrastructure of the crossed isthmotectal projection in Xenopus frogs. Journal of Comparative Neurology 292, 246–254.CrossRefGoogle ScholarPubMed
Wallace, M.T., Ricciuti, A.J. & Gruberg, E.R. (1990). Nucleus isthmi: Its contribution to tectal acetylcholinesterase and choline acetyltransferase in the frog Rana pipiens. Neuroscience 35, 627–636.CrossRefGoogle ScholarPubMed