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Inhibition of Amitrole-5-C14 Accumulation in Salmonella typhimurium by Purines

Published online by Cambridge University Press:  12 June 2017

J. L. Hilton  and
D. D. Kaufman
J. L. Hilton
Affiliation:
Crops Research Division, Agricultural Research Service, U. S. Department of Agriculture, Beltsville, Maryland
D. D. Kaufman
Affiliation:
Crops Research Division, Agricultural Research Service, U. S. Department of Agriculture, Beltsville, Maryland
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Abstract

Amitrole (3-amino-1,2,4-triazole) is absorbed and actively bound to non-physiological sites in Salmonella typhimurium. Accumulation of amitrole is inhibited by purines; but the effect does not seem to explain adenine protection against growth inhibition by amitrole. Guanine, xanthine, and hypoxanthine cannot replace adenine in growth protection but do inhibit accumulation of amitrole in the bacterial cells.

Type
Research Article
Information
Weeds , Volume 15 , Issue 3 , July 1967 , pp. 255 - 258
Copyright
Copyright © 1967 Weed Science Society of America 

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References

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