Hostname: page-component-cd9895bd7-p9bg8 Total loading time: 0 Render date: 2024-12-27T22:10:20.965Z Has data issue: false hasContentIssue false
  • English
  • Français

Chicken infectious anaemia, an immunosuppressive disease of poultry birds

Published online by Cambridge University Press:  13 November 2014

S. UMAR ,
S. ULLAH ,
M. YAQOOB ,
M.A.A. SHAH  and
M. DUCATEZ
S. UMAR
Affiliation:
Faculty of Veterinary & Animal Sciences, Arid Agriculture University, Rawalpindi, Pakistan Institut National de la Recherche Agronomique, UMR 1225 IHAP, Toulouse, France Université de Toulouse, INP, ENVT, 31076, Toulouse, France
S. ULLAH
Affiliation:
NUST Centre of Virology & Immunology, National University of Science and Technology Islamabad, Pakistan
M. YAQOOB
Affiliation:
Faculty of Veterinary & Animal Sciences, Arid Agriculture University, Rawalpindi, Pakistan
M.A.A. SHAH*
Affiliation:
Faculty of Veterinary & Animal Sciences, Arid Agriculture University, Rawalpindi, Pakistan School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China
M. DUCATEZ
Affiliation:
Institut National de la Recherche Agronomique, UMR 1225 IHAP, Toulouse, France Université de Toulouse, INP, ENVT, 31076, Toulouse, France
*
Corresponding author: alishah521@gmail.com
Get access

Abstract

Immunosuppressive viral diseases have become a major cause of mortality and economic losses in poultry industry mainly because of increased susceptibility of second bacterial infections and low response to vaccination. Nowadays chicken infectious anaemia is a great threat to poultry industry due to the large number of deaths and immuno-suppression it causes. Chicken anaemia virus replicates in erythroid and lymphoid progenitor cells, causing an apparent, sub-clinical infection that leads to depletion of these cells with consequent immunosuppressive effects. This review will summarise the currently available information about the chicken infectious anaemia virus and subsequent disease. Secondly, it will address the possible immune-pathogenic and immune-suppressive effects of chicken infectious anaemia in birds, including commercial poultry. Finally, the future prospects of vaccination against chicken infectious anaemia and other possible novel methods for the control of chicken anaemia virus are discussed.

Keywords

chicken anaemia viruslymphoid tissueimmunopathogenesispoultry
Type
Review Article
Information
World's Poultry Science Journal , Volume 70 , Issue 4 , December 2014 , pp. 759 - 766
Copyright
Copyright © World's Poultry Science Association 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

ADAIR, B.M. (2000) Immunopathogenesis of CIAV infection. Developmental and Comparative Immunology 24: 247-255.Google Scholar
ADAIR, B.M. (1996) Virus induced immunosuppression, in DAVIDSON, T.F., MORRIS, T.R. & PAYNE, L.N. (Eds) Poultry Immunology, pp. 301-315 (Abingdon, Oxon: Carfax Publishing Company).Google Scholar
ADAIR, B.M. and MCNULTY, M.S. (1997) Lymphocyte transformation and lymphokine production during CIAV infection, in: SCHIJNS, V.E.C.J. & HORZINEK, M.C. (Eds) Cytokines in Veterinary Medicine, pp. 301-310 (Wallingford: CAB International).Google Scholar
BALAMURUGAN, V. and KATARIA, J.M. (2006) Economically Important Non-oncogenic Immunosuppressive Viral Diseases of Chicken-Current Status. Veterinary Research Communications 30: 541-566.Google Scholar
BOUNOUS, D.I., GOODWIN, M.A., BROOKS, R.L., LAMICHHANE, C.M., CAMPAGNOLI, R.P., BROWN, CARDONA, C., LUCIO, B., O'CONNELL, P., JAGNE, J. and SCHAT, K.A. (2000) Humoural immune responses to chicken infectious anaemia virus in three strains of chickens in a closed flock. Avian Diseases 44: 661-667.Google Scholar
BRENTANO, L., LAZZARIN, S., BASSI, S.S., KLEIN, T.A.P. and SCHAT, K.A. (2005) Detection of CIAV in the gonads and in the progeny of broiler breeder hens with high neutralising antibody titres. Veterinary Microbiology 105: 65-73.Google Scholar
CARRIE, J. and SCHAT, K.A. (2003) Infection with CIAV impairs the generation of pathogen-specific cytotoxic T lymphocytes. Immunology 109: 283-294.Google Scholar
DE HERDT, P., VAN DEN BOSCH, G., DUCATELLE, R., UYTTEBROEK, E. and SCHRIER, C. (2001) Epidemiology and significance of chicken infectious anaemia virus infections in broilers and broiler parents under nonvaccinated European circumstances. Avian Diseases 45: 706-708.Google Scholar
DAVIDSON, I., ARTZI, N., SHKODA, I., LUBLIN, A., LOEB, E. and SCHAT, K.A. (2008) The contribution of feathers in the spread of chicken anaemia virus. Virus Research 132: 152-159.Google Scholar
DHAMA, K., KATARIA, J.M., DASH, B.B., SENTHILKUMAR, N. and TOMAR, O. (2002) Chicken infectious anaemia (CIA): a review. Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases 23: 1-15.Google Scholar
DRÉN, C.N., KANT, A., VAN ROOZELAAR, D.J., HARTOG, L., NOTEBORN, M.H. and KOCH, G. (2000) Studies on the pathogenesis of chicken infectious anaemia virus infection in six-week-old SPF chickens. Acta Veterinaria Hungarica 48: 455-467.Google Scholar
FUSSELL, L.W. (1998) Poultry industry strategies for control of immunosuppressive diseases. Journal of Poultry Science 77: 1193-1196.Google Scholar
GURUNATHAN, S., KLINMAN, D. and SEDER, R. (2000) DNA vaccines: immunology, application, and optimisation. Annual Review of Immunology 18: 927-974.Google Scholar
HAGOOD, L.T., KELLY, T.F., WRIGHT, J.C. and HOERR, F.J. (2000) Evaluation of chicken infectious anaemia virus and associated risk factors with disease and production losses in broilers. Avian Diseases 44: 803-808.Google Scholar
HERMANN, J., KOSKI, D., TAYLOR, S. and GATEWOOD, D. (2012) Evaluation of the analytical sensitivity of a polymerase chain reaction assay for the detection of chicken infectious anaemia virus in avian vaccines. Biologicals 40: 266-269.Google Scholar
HU, L.B., LUCIO, B. and SCHAT, K.A. (1993) Depletion of CD4+ and CD8+ T lymphocyte subpopulations by CIA-1, a chicken infectious anaemia virus. Avian Diseases 37: 492-500.Google Scholar
HUSSEIN, H.A., YOUSSEF, M.M., OSMAN, A., EL-EBIARY, E.A. and SHALABY, M.A. (2003) Immunopathogenesis of attenuated strain of chicken infectious anaemia virus in one-day-old specific-pathogen-free chicks. Egypt Journal of Immunology 10: 89-102.Google Scholar
KUSCU, B. and GUREL, A. (2008) Lesions in the thymus and bone marrow in chicks with experimentally induced chicken infectious anaemia disease. Journal of Veterinary Sciences 9: 15-23.Google Scholar
MARKOWSKI-GRIMSRUD, C.J. and SCHAT, K.A. (2003) Infection with CIAV impairs the generation of pathogen-specific cytotoxic T lymphocytes. Immunology 109: 283-294.Google Scholar
MILLER, M.M., EALEY, K.A., OSWALD, W.B. and SCHAT, K.A. (2003) Detection of CIAV DNA in embryonal tissues and egg shell membranes. Avian Diseases 47: 662-671.Google Scholar
MOEINI, H., OMAR, A.R., RAHA, A.R. and YUSOFF, K. (2011) Improving the potency of DNA vaccine against CIAV (CAV) by fusing VP1 protein of CIAV to Marek's Disease Virus (MDV) Type-1 VP22 protein. Virology Journal 8: 119.Google Scholar
NOTEBORN, H.M. (2004) CIAV induced apoptosis: underlying molecular mechanisms. Veterinary Microbiology 98: 89-94.Google Scholar
NOTEBORN, M.H.M. and KOCH, G. (1995) CIAV infection: molecular basis of pathogenicity Avian Pathology 24: 11-13.Google Scholar
OLUWAYELU, D.O., OLALEYE, O.D. and TODD, D. (2010) Biological characterisation of Nigerian CIAV isolates. African Journal of Medical Science 39: 21-26.Google Scholar
SANJAY, G.D., KLINMAN, M. and SEDER, R.A. (2000) DNA Vaccines: Immunology, Application, and Optimisation. Annual Review of Immunology 18: 927-974.Google Scholar
SCHAT, K.A. (2009) Chicken anaemia virus. Curr Top Microbiol Immunology 331: 151-183.Google Scholar
SCHAT, K.A. and VAN SANTEN, V.L. (2008) Chicken Infectious Anaemia, in: SAIF, Y.M., FADLY, A.M., GLISSEN, J.R., MCDOUGALD, L.R., NOLAN, L.K. & SWAYNE, D.E. (Eds) Diseases of Poultry, 12th Edition, pp. 211-235 (Wiley-Blackwell).Google Scholar
SCHAT, K.A., MARTINS, N.R., O'CONNELL, P.H. and PIEPENBRINK, M.S. (2011) Immune complex vaccines for chicken infectious anaemia virus . Avian Diseases 55: 90-96.Google Scholar
SENTHILKUMAR, N., KATARIA, J.M., DHAMA, K., RAHUL, S. and BARADHWAJ, N. (2006) Biological and molecular characterisation of CIAV isolates of Indian origin. Virus Research 118: 78-86.Google Scholar
SHAH, M.A.A. (2013) DNA vaccines as sustainable Coccidiosis control strategies in chickens. Science Letters 1: 1-4.Google Scholar
SHAH, M.A.A., XU, L., YAN, R., SONG, X. and LI, X. (2011) Construction of DNA vaccines encoding Eimeria acervulina cSZ-2 with chicken IL-2 and IFN-γ and their induced immunity against poultry Coccidiosis. Research in Veterinary Science. 90: 72-77.Google Scholar
SHAH, M.A.A., XU, L., YAN, R., SONG, X. and LI, X. (2010) The DNA induced protective immunity with chicken interferon gamma against poultry coccidiosis. Parasitology Research 107: 747-750.Google Scholar
SMYTH, J.A., MOFFETT, D.A., CONNOR, T.J. and MCNULTY, M.S. (2006) CIAV inoculated by the oral route causes lymphocity depletion in the thymus in 3-week-old and 6-week-old chickens. Avian Pathology 35: 254-259.Google Scholar
SOMMER, F. and CARDONA, C. (2003) CIAV in broilers: Dynamics of the infection in two commercial broiler flocks. Avian Diseases 47: 1466-1473.Google Scholar
SONG, X., XU, L., YAN, R., HUANG, X., SHAH, M.A.A. and LI, X. (2009) The optimal immunisation procedure of DNA vaccine pcDNA-TA4-IL-2 of Eimeria tenella, its cross immunity to Eimeria necatrix and Eimeria acervulina. Veterinary Parasitology 159: 30-36.Google Scholar
TAN, J. and TANNOCK, G. (2005) Role of viral load in the pathogenesis of chicken anaemia virus. Journal of General Virology 86: 1327-1333.Google Scholar
TODD, D. and MCNULTY, M.S. (2007) Circoviridae, in: PATTISON, M., MCMULLIN, P., BRADBURY, J. & ALEXANDER, D. (Eds) Poultry Diseases, 6th Edition, pp. 398-405 (Saunders, Elsevier).Google Scholar
TODD, D. (2000) Circoviruses: immunosuppressive threat to avian species; a review. Avian Pathology 29: 373-394.Google Scholar
ULLAH, S., RIAZ, N., UMAR, S. and SHAH, M.A.A. (2013) DNA Vaccines against Avian Influenza: current research and future prospects. World's Poultry Science Journal 69: 125-133.Google Scholar
VAN SANTEN, V.L., JOINER, K.S., MURRAY, C., PETRENKO, N., HOERR, F.J. and TORO, H. (2004) Pathogenesis of Chicken Anaemia virus: Comparison of the oral and the intramuscular routes of infection. Avian Diseases 48: 494-504.Google Scholar
XU, Q., SONG, X., XU, L., YAN, R., SHAH, M.A.A. and LI, X. (2008) Vaccination of chickens with a chimeric DNA vaccine encoding Eimeria tenella TA4 and chicken IL-2 induces protective immunity against coccidiosis. Veterinary Parasitology 156: 319-323.Google Scholar
YAMAGUCHI, S., IMADA, T., KAJI, N., MASE, M., TSUKAMOTO, K., TANIMURA, N. and YUASA, N. (2001) Identification of a genetic determinant of pathogenicity in chicken anaemia virus. Journal of General Virology 82: 1233-1238.Google Scholar
YUASA, N. and YOSHIDA, I. (1983) Experimental egg transmission of chicken anaemia agent. Institute of Animal Health Q ( Tokyo) 23: 99-100.Google Scholar