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The major histocompatibility complex and its role in poultry production

Published online by Cambridge University Press:  18 September 2007

Jean E. Sander
Jean E. Sander
Affiliation:
Department of Avian Medicine, College of Veterinary Medicine, Athens, Georgia 30602-4875, USA
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Abstract

The major histocompatibility complex (MHC) is a group of genes present in all vertebrates. The chicken MHC is broken into three distinct regions, each of which codes for certain gene products. These antigens are known to influence a variety of biological functions including fowl cholera, Marek's disease, Rous sarcoma virus, lymphoid leukosis and coccidiosis. Fertility, embryonic mortality, hatchability, and egg production are some of the production parameters linked to this gene complex. Blood groups serve as markers for these regions, offering a means of genetic screening.

Keywords

Genesproteinsdisease resistancechickens
Type
Research Article
Information
World's Poultry Science Journal , Volume 49 , Issue 2 , July 1993 , pp. 132 - 138
Copyright
Copyright © Cambridge University Press 1993

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References

Bacon, L.D. (1987) Influence of the major histocompatibility complex on disease resistance and productivity. Poultry Science 66: 802–811Google Scholar
Bacon, L.D., Whitter, R.L., Crittenden, L.B., Fadly, A. and Motta, J.B. (1981) Haplotype influence on Marek's disease, Rous sarcoma, and lymphoid leucosis virus-induced tumours in chickens. Poultry Science 60: 1132–1139CrossRefGoogle Scholar
Bloom, S.E., Briles, W.E., Briles, R.W., Delany, M.E. and Dietert, R.R. (1987) Chromosomal localization of the major histocompatibility (B) complex (MHC) and its expression in chickens aneuploid for the major histocompatibility complex/ribosomal deoxyribonucleic acid microchromosome. Poultry Science 66: 782–789Google Scholar
Bourlet, Y., Béhar, G., Guillemot, F., Fréchin, N., Billault, A., Chaussé, A. et al. (1988) Isolation of chicken major histocompatibility complex class II (B-L) β chain sequences: comparison with mammalian β chains and expression in lymphoid organs. EMBO Journal 7: 1031–1039Google Scholar
Briles, W.E. and Briles, R.W. (1987) Genetics and classification of the major histocompatibility complex antigens of the chicken. Poultry Science 66: 776–781CrossRefGoogle ScholarPubMed
Briles, W.E., McGibbon, W.H. and Irwin, M.R. (1950) On multiple alleles affecting cellular antigens in the chicken. Genetics 35: 633–652Google Scholar
Dietert, R.R. (1987) Introduction: the major histocompatibility complex as a communication gene complex. Poultry Science 66: 774–775Google Scholar
Gill, T.J. III, Siew, S. and Kunz, H.W. (1983) Major histocompatibility complex (MHC)-linked genes affecting development. Journal of Experimental Zoology 228: 325–345Google Scholar
Goto, R., Miyada, C.G., Young, S., Wallace, R.B., Abplanalp, H., Bloom, S.E. et al. (1988) Isolation of a cDNA clone from the B-G subregion of the chicken histocompatibility (B) complex. Immunogenetics 27: 102–109Google Scholar
Guillemot, F., Billault, A., Pourquié, O., Béhar, A., Chaussé, A., Zoorob, R. et al. (1988) A molecular map of the chicken major histocompatibility complex: the class II β genes are closely linked to the class I genes and the nucleolar organizer. EMBO Journal 7: 2775–2785Google Scholar
Guillemot, F., Turmel, P., Charron, D., Ledouarin, N. and Auffray, C. (1986) Structure, biosynthesis, and polymorphism of chicken MHC class II (B-L) antigens and associated molecules. Journal of Immunology 137: 1251–1257Google Scholar
Hála, K., Boyd, R. and Wick, G. (1981) Chicken major histocompatibility complex and disease. Scandinavian Journal of Immunology 14: 607–616Google Scholar
Lamont, S.J., Bolin, C. and Cheville, N. (1987a) Genetic resistance to fowl cholera is linked to the major histocompatibility complex. Immunogenetics 25: 284–289Google Scholar
Lamont, S.J., Hou, Y.H., Young, B.M. and Nordskog, A.W. (1987b) Differences in major histocompatibility complex gene frequencies associated with feed efficiency and laying performance. Poultry Science 66: 1064–1066CrossRefGoogle ScholarPubMed
Longnecker, B.M. and Mosmann, T.R. (1981). Structure and properties of the major histocompatibility complex of the chicken. Speculations on the advantages and evolution of polymorphism. Immunogenetics 13: 1–23CrossRefGoogle Scholar
MacCubbin, D.L. and Schierman, L.W. (1986) MHC-restricted cytotoxic response of chicken T cells: expression, augmentation, and clonal characteristics. Journal of Immunology 136: 12–16CrossRefGoogle Scholar
Martin, A., Gross, W.B., Dunnington, E.A., Briles, R.W., Briles, W.E. and Siegel, P.B. (1986) Resistance to natural and control exposures to Eimeria tenella: genetic variation and alloantigen systems. Poultry Science 65: 1847–1852Google Scholar
Nordskog, A.W., Pevzer, I.Y. and Lamont, S.J. (1987) Subregions and functions of the chicken major histocompatibility complex. Poultry Science 66: 790–794Google Scholar
Pink, J.R.L., Droege, W., Hála, K., Miggiano, V.C. and Ziegler, H. (1977) A three-locus model of the chicken major histocompatibility complex. Immunogenetics 5: 203–216Google Scholar
Schierman, L.W. and Collins, W.M. (1987) Influence of the major histocompatibility complex on tumour regression and immunity in chickens. Poultry Science 66: 812–818Google Scholar
Simonsen, M. (1981) The major histocompatibility complex in a bird's eye view. In: Immunobiology of the Major Histocompatibility Complex (Eds Zaleski, M.B., Abeyounis, C.J. and Kano, K.). Karger, Basel and New York, pp. 192–201Google Scholar
Vainio, O., Toivanen, P. and Toivanen, A. (1987) Major histocompatibility complex and cell cooperation. Poultry Science 66: 795–801CrossRefGoogle ScholarPubMed
Wagner, R.P., Judd, B.H., Sanders, B.G. and Richardson, R.H. (1980) Introduction to Modern Genetics. Wiley, New YorkGoogle Scholar