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Probiotic micro-organisms: 100 years of innovation and efficacy; modes of action

Published online by Cambridge University Press:  27 August 2010

B. VILÀ ,
E. ESTEVE-GARCIA  and
J. BRUFAU
B. VILÀ*
Affiliation:
IRTA, Monogastric Nutrition, Mas de Bover, Ctra. Reus El Morell km 3.8, 43120 Constantí, Spain
E. ESTEVE-GARCIA
Affiliation:
IRTA, Monogastric Nutrition, Mas de Bover, Ctra. Reus El Morell km 3.8, 43120 Constantí, Spain
J. BRUFAU
Affiliation:
IRTA, Monogastric Nutrition, Mas de Bover, Ctra. Reus El Morell km 3.8, 43120 Constantí, Spain
*
Corresponding author: borja.vila@irta.cat
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Abstract

Benefits from probiotic micro-organisms have been recognised for over 100 years, and as being useful in poultry for 50 years. Fuller (1989) redefined probiotics as ‘a live microbial feed supplement which beneficially affects the host animal by improving its intestinal microbial balance’. Benefits derived from this improved intestinal microbial balance could be reflected in performance or prevention of pathogen colonisation. Probiotic micro-organisms use in poultry production has been widely accepted and new opportunities arose from the 2006 EU ban on antimicrobial growth promoters. The majority of microbial products for compound feeds are made up from a relatively small number of micro-organisms that are normally present in the GI tract. They include non-sporulated bacteria, sporulated bacteria, fungi or yeasts; and presented from single to multi-strain products. A review on the proposed modes of action is presented including recent approaches to quorum sensing interference.

Keywords

probiotic micro-organismsdirect fed microbialspoultrymodes of action
Type
Review Article
Information
World's Poultry Science Journal , Volume 66 , Issue 3 , September 2010 , pp. 369 - 380
Copyright
World's Poultry Science Association 2010

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References

ANADÓN, A., ROSA MARTINEZ-LARRAÑAGA, M. and ARANZAZU MARTINEZ, M. (2006) Probiotics for animal nutrition in the European Union. Regulation and safety assessment. Regulatory Toxicology and Pharmacology 45: 91-95.CrossRefGoogle ScholarPubMed
AUGER, S. KRIN, E., , AYMERICH, S. and GOHAR, M. (2006) Autoinducer 2 affects biofilm formation by Bacillus cereus. Applied and Environmental Microbiology 72: 937-941.CrossRefGoogle ScholarPubMed
BARROW, P.A. (1992) Probiotics for chickens, in: FULLER, R. (Ed) Probiotics. The scientific basis, pp. 225-257 (Chapman & Hall, London).Google Scholar
CALVO TORRAS, M.A., ADELANTADO, C., JIMÉNEZ, G., CASTILLO, M., MEYER, G., BLANCH, and A, (2007) In vitro inhibition/stimulation of the growth capacity of gut bacteria by Toyocerin (Bacillus cereus var. toyoi), in: PLITZNER, C., KRAFT, M. & WINDISCH, W. (Eds.) BOKU-Symposium Tierernährung, pp. 218-222 (Wien).Google Scholar
CERDÀ-CUÉLLAR, M., BADIOLA, I. and CASTILLO, M. (2009) In vitro degradation of N-acyl-L-homoserine lactones by Bacillus cereus var toyoi. XI International Symposium on Digestive Physiology of Pigs, Montbrió del Camp, Spain, S2.36.Google Scholar
COPPOLA, M.D.M., CONCEIÇÃO, F.R. and GIL-TURNES, C. (2005) Effect of Saccharomyces boulardii and Bacillus cereus var. toyoi on the humoral and cellular response of mice to vaccines. Food and Agricultural Immunology 16: 213-219.CrossRefGoogle Scholar
DELBECQUE, J. (1991) Ecología microbiana intestinal, biorregulación y aplicaciones prácticas. Anaporc 102: 32-52.Google Scholar
DIBNER, J.J. and RICHARDS, J.D. (2005) Antibiotic growth promoters in agriculture: history and mode of action. Poultry Science 84: 634-643.CrossRefGoogle ScholarPubMed
DUNHAM, H.J., WILLIAMS, C., EDENS, F.W., CASAS, I.A. and DOBROGOSZ, W.J. (1993) Lactobacillus reuteri immunomodulation of stressor-associated diseases in newly hatched chickens and turkeys. Poultry Science 72: 103.Google Scholar
EDENS, F.W. (2003) An alternative for antibiotic use in poultry: probiotics. Revista Brasileira de Ciência Avícola (online) 5: 75-97.CrossRefGoogle Scholar
EFSA, (2005) The EFSA's 2nd Scientific Colloquium Report - QPS. European Food Safety Authority.CrossRefGoogle Scholar
FLINT, J.F. and GARNER, M.R. (2009) Feeding beneficial bacteria: A natural solution for increasing efficiency and decreasing pathogens in animal agriculture. Journal of Applied Poultry Research 18: 367-378.CrossRefGoogle Scholar
FOX, S.M. (1988) Probiotics: intestinal inoculants for production animals. Veterinary Medicine 1988: 806-830.Google Scholar
FULLER, R. (1977) The importance of lactobacilli in maintaining normal microbial balance in the crop. British Poultry Science 18: 85-94.CrossRefGoogle ScholarPubMed
FULLER, R. (1989) Probiotics in man and animals. Journal of Applied Bacteriology 66: 365-378.Google Scholar
GARLICH, J.D. (1999) Microbiología del tracto intestinal: los probióticos. Tecnología Avipecuaria en Latinoamérica 13: 24-28.Google Scholar
HIGGINS, S.E., ERF, G.F., HIGGINS, J.P., HENDERSON, S.N., WOLFENDEN, A.D., GAONA-RAMIREZ, G. and HARGIS, B.M. (2007) Effect of Probiotic Treatment in Broiler Chicks on Intestinal Macrophage Numbers and Phagocytosis of Salmonella Enteritidis by Abdominal Exudate Cells. Poultry Science 86: 2315-2321.CrossRefGoogle ScholarPubMed
JADAMUS, A., VAHJEN, W., SCHÄFER, K. and SIMON, O. (2002) Influence of the probiotic strain Bacillus cereus var. toyoi on the development of enterobacterial growth and on selected parameters of bacterial metabolism in digesta samples of piglets Journal of Animal Physiology and Animal Nutrition 86: 42-54.CrossRefGoogle ScholarPubMed
JADAMUS, A., VAHJEN, W. and SIMON, O. (2000) Influence of the probiotic bacterial strain, Bacillus cereus var. toyoi, on the development of selected microbial groups adhering to intestinal mucosal tissues of piglets. Journal of Animal Feed Sciences 9: 347-362.CrossRefGoogle Scholar
JERNIGAN, M.A., MILES, R.D. and ARAFA, A.S. (1985) Probiotics in poultry nutrition - a review. Worlds Poultry Science Journal 41: 99-107.CrossRefGoogle Scholar
KABIR, S.M.L., RAHMAN, M.M., RAHMAN, M.B., RAHMAN, M.M. and AHMED, S.U. (2004) The dynamics of probiotics on growth performance and immune response in broilers. International Journal of Poultry Science 3: 361-364.Google Scholar
KHAJARERN, J. and RATANASETHAKUL, C. (1998) Probiotics in breeder feed. World Poultry 14: 18-19.Google Scholar
KHAKSEFIDI, A. and GHOORCHI, T. (2006) Effect of Probiotic on Performance and Immunocompetence in Broiler Chicks. The Journal of Poultry Science 43: 296-300.CrossRefGoogle Scholar
KOLB, H. (1955) Die Behandlung akuter Infekte unter dem Gesichtswinkel der Prophylaxe chronischer Leiden. Über die Behandlung mit physiologischen Bakterien. Microecology and Therapy 1: 15-19.Google Scholar
LEBEER, S., DE KEERSMAECKER, S.C.J., VERHOEVEN, T.L.A., FADDA, A.A., MARCHAL, K. and VANDERLEYDEN, J. (2007) Functional Analysis of luxS in the Probiotic Strain Lactobacillus rhamnosus GG Reveals a Central Metabolic Role Important for Growth and Biofilm Formation. Journal of Bacteriology 189: 860-871.CrossRefGoogle ScholarPubMed
LEV, M. and BRIGGS, C.A.E. (1956) The gut flora of the chick. 2. The establishment of the flora. Journal of Applied Bacteriology 19: 224-230.CrossRefGoogle Scholar
LILLEY, D.M. and STILLWELL, R.H. (1965) Probiotics: growth promotion factors produced by micro-organisms. Science 147: 747-748.CrossRefGoogle Scholar
MEDELLIN-PEÑA, M.J., WANG, H., JOHNSON, R., ANAND, S. and GRIFFITHS, M.W. (2007) Probiotics Affect Virulence-Related Gene Expression in Escherichia coli O157:H7. Applied and Environmental Microbiology 73: 4259-4267.CrossRefGoogle ScholarPubMed
MEDINA-MARTINEZ, M.S., UYTTENDAELE, M., RAJKOVIC, A., NADAL, P. and DEBEVERE, J. (2007) Degradation of N-Acyl-L-Homoserine Lactones by Bacillus cereus in Culture Media and Pork Extract. Applied and Environmental Microbiology 73: 2329-2332.CrossRefGoogle ScholarPubMed
MICHAEL, B., SMITH, J.N., SWIFT, S., HEFFRON, F. and AHMER, B.M.M. (2001) SdiA of Salmonella enterica Is a LuxR Homolog That Detects Mixed Microbial Communities. Journal of Bacteriology 183: 5733-5742.CrossRefGoogle ScholarPubMed
MILES, R.D. and BOOTWALLA, S.M. (1991) Direct-fed microbials in animal production, in: N.F.I. ASSOCIATION (Ed.) Direct-fed microbials in animal production. A Review, pp. 117-132 (West Des Moines, Iowa, USA).Google Scholar
NAHASHON, S.N., NAKAUE, H.S., SNYDER, S.P. and MIROSH, L.W. (1994) Performance of Single Comb White Leghorn layers fed corn-soybean meal and barley-corn-soybean meal diets supplemented with a direct-fed microbial. Poultry Science 73: 1712-1723.CrossRefGoogle ScholarPubMed
NURMI, E. and RANTALA, M. (1973) New aspects of Salmonella infection in broiler production. Nature 241: 210-211.CrossRefGoogle ScholarPubMed
OSCÁRIZ, J.C., LASA, I. and PISABARRO, A.G. (1999) Detection and characterization of cerein 7, a new bacteriocin produced by Bacillus cereus with a broad spectrum of activity. FEMS Microbiology Letters 178: 337.CrossRefGoogle ScholarPubMed
PARKER, R.B. (1974) Probiotics: the other half of the antibiotic story. Animal Nutrition and Health 29: 4-8.Google Scholar
PATTERSON, J.A. and BURKHOLDER, K.M. (2003) Application of prebiotics and probiotics in poultry production. Poultry Science 82: 627-631.CrossRefGoogle ScholarPubMed
REVOLLEDO, L., FERREIRA, A.J.P. and MEAD, G.C. (2006) Prospects in Salmonella Control: Competitive Exclusion, Probiotics, and Enhancement of Avian Intestinal Immunity. Journal of Applied Poultry Research 15: 341-351.CrossRefGoogle Scholar
RISØEN, P.A., RØNNING, P., HEGNA, I.K. and KOLSTØ, A.-B. (2004) Characterization of a broad range antimicrobial substance from Bacillus cereus Journal of Applied Microbiology 96: 648.CrossRefGoogle Scholar
RUSCH, V. (2002) Probiotics and definitions: a short overview, in: HEIDT, P.J., MIDTVEDT, T., RUSCH, V. & VAN DER WAAIJ, D. (Eds.) Probiotics: Bacteria and Bacterial Fragments as Immunomodulatory agents, pp. 1-4 (Old Hernorn University, Herborn-Dill, Germany).Google Scholar
SCAN, (2000) Report of the Scientific Committee on Animal Nutrition on the assessment under directive 87/153/EEC of the efficacy of micro-organisms used as feed additives (expressed on 18 February 2000) Scientific Committee on Animal Nutrition, Brussels, Belgium, 9.Google Scholar
SCAN, (2003) Position paper of the Scientific Committee on Animal Nutrition on Safety Assessment and Regulatory Aspects of Micro-organisms in Feed and Food Applications Scientific Committee on Animal Nutrition.Google Scholar
SCHAREK, L., ALTHERR, B.J., TÖLKE, C. and SCHMIDT, M.F.G. (2007a) Influence of the probiotic Bacillus cereus var. toyoi on the intestinal immunity of piglets. Veterinary Immunology and Immunopathology 120: 136-147.CrossRefGoogle ScholarPubMed
SCHAREK, L., GUTH, J., FILTER, M. and SCHMIDT, M.F.G. (2007b) Impact of the probiotic bacteria Enterococcus faecium NCIMB 10415 (SF68) and Bacillus cereus var. toyoi NCIMB 40112 on the development of serum IgG and faecal IgA of sows and their piglets. Archives of Animal Nutrition 61: 223-234.CrossRefGoogle ScholarPubMed
SCHAUDER, S. and BASSLER, B.L. (2001) The languages of bacteria. Genes and Development 15: 1468-1480.CrossRefGoogle ScholarPubMed
SCHIERACK, P., WALK, N., REITER, K., WEYRAUCH, K.D. and WIELER, L.H. (2007) Composition of intestinal Enterobacteriaceae populations of healthy domestic pigs. Microbiology 153: 3830-3837.CrossRefGoogle ScholarPubMed
SCHNEITZ, C. (2005) Competitive exclusion in poultry--30 years of research. Food Control 16: 657-667.CrossRefGoogle Scholar
SIMON, O. and JADAMUS, A. (2002) Probiotics and prebiotics. 11th European Poultry Conference, European Federation Worlds Poultry Science Association, Bremen, Germany, 1-11.Google Scholar
SIMON, O., JADAMUS, A. and VAHJEN, W. (2002) The secret life of a probiotic Bacillus. Feed Mix 10: 1-5.Google Scholar
SNEL, J., HARMSEN, H.J.M., WIELEN, P.W.J.J.V.D. and WILLIAMS, B.A. (2002) Dietary strategies to influence the gastrointestinal microflora of young animals, and its potential to improve intestinal health, in: BLOK, M.C., VAHL, H.A., LANDE, L.D., BRAAK, A.E.V.D., HEMKE, G. & HESSING, M. (Eds.) Nutrition and health of the gastrointestinal tract, pp. 37-69 (Wageningen Academic Publishers, Wageningen).Google Scholar
SÖGAARD, H. and SUHR-JESSEN, T. (1990) Microbials for feed: beyond lactic acid bacteria. Feed International 1990: 32-36.Google Scholar
SPERTI, G.S. (1971) Probiotics. CT Avi Publishing Co, West Point.Google Scholar
TARAS, D., VAHJEN, W., MACHA, M. and SIMON, O. (2005) Response of performance characteristics and fecal consistency to long-lasting dietary supplementation with the probiotic strain Bacillus cereus var. toyoi to sows and piglets. Archives of Animal Nutrition 59: 405-417.CrossRefGoogle ScholarPubMed
VANBELLE, M., TELLER, E. and FOCANT, M. (1990) Probiotics in animal nutrition: a review. Archives of Animal Nutrition, Berlin 40: 543-567.Google ScholarPubMed
VILÀ, B., FONTGIBELL, A., BADIOLA, I., ESTEVE-GARCIA, E., JIMENEZ, G., CASTILLO, M. and BRUFAU, J. (2009) Reduction of Salmonella enterica var. Enteritidis colonisation and invasion by Bacillus cereus var. toyoi inclusion in poultry feeds. Poultry Science 88: 975-979.CrossRefGoogle ScholarPubMed
ZULKIFLI, I., ABDULLAH, N., AZRIN, N.M. and HO, Y.W. (2000) Growth performance and immune response of two commercial broiler strains fed diets containing Lactobacillus cultures and oxytetracycline under heat stress conditions. British Poultry Science 41: 593-597.CrossRefGoogle ScholarPubMed