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Development and loss of the ability of mouse oolemma to fuse with spermatozoa

Published online by Cambridge University Press:  26 September 2008

Maurizio Zuccotti ,
Anna Piccinelli ,
Nicola Marziliano ,
Silvia Mascheretti  and
Carlo Alberto Redi
Maurizio Zuccotti*
Affiliation:
Dipartimento di Biologia Arimale and centro di studio per I'Istochimic del CNR, University of pavia, Italy
Anna Piccinelli
Affiliation:
Dipartimento di Biologia Arimale and centro di studio per I'Istochimic del CNR, University of pavia, Italy
Nicola Marziliano
Affiliation:
Dipartimento di Biologia Arimale and centro di studio per I'Istochimic del CNR, University of pavia, Italy
Silvia Mascheretti
Affiliation:
Dipartimento di Biologia Arimale and centro di studio per I'Istochimic del CNR, University of pavia, Italy
Carlo Alberto Redi
Affiliation:
Dipartimento di Biologia Arimale and centro di studio per I'Istochimic del CNR, University of pavia, Italy
*
Maurizio Zuccotti, Dipartimento di Biologia Animale, Laboratorio Istologia ed Embriologia, University of Pavia, Piazza Botta 10, I-27100 Pavia, Italy. Telephone: +/382/386323. Fax: +/382/386290. e-Mail: ANTRO at IPVCCN.BITNET.
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Summary

To further our Knowledge on the mechanisms and molecules involved in mouse sperm–oocyte plasma membrane interaciton, exteraction, experiments were carried out to determine the stage during oogenesis at which an oocte acquires the capacity ot fuse with acrosome-reacted sperm. Zona-ferr oocytes 10 μm in diametes do not fuse with sperm. Oolemma fusibility is first acquired when the oocyte reaches about 20μm in diameter. Fusibility is maniatained even after fertilisation has accurred and is lost completely by the 4–cell stage.

Keywords

FertilisationMembrane fusionOolemmapolyspermy block
Type
Article
Information
Zygote , Volume 2 , Issue 4 , November 1994 , pp. 333 - 339
Copyright
Copyright © Cambridge University Press 1994

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