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Does the meiotic spindle really predicts embryo implantation and live birth rates? An update

Published online by Cambridge University Press:  05 December 2018

Sabela García-Oro Open the ORCID record for Sabela García-Oro [Opens in a new window]  and
Diana Valverde
Sabela García-Oro*
Affiliation:
Equipo Ron – Hospital Quironsalud A Coruña, C/Londres 2, 15009 A Coruña, Spain
Diana Valverde
Affiliation:
Department Biochemistry, Genetics and Immunology, Faculty of Biology, University of Vigo, Campus As Lagoas Marcosende S/N, 36310 Vigo, Spain Instituto de Investigación Sanitaria Galicia Sur, Pontevedra, Spain
*
Address for correspondence: Sabela García-Oro. Equipo Ron – Hospital Quironsalud A Coruña, C/Londres 2, 15009 A Coruña, Spain. E-mail: sabela.oro@quironsalud.es
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Summary

The aim of this study was to determine the capacity of the meiotic spindle (MS) to predict embryo implantation and live birth rates. For this purpose, we performed a broad systematic literature search. Of all publications retrieved, only those in which the implantation rates were related to some characteristics of the MS were evaluated. Despite the different methodology used in all the chosen studies, presence of the MS in oocytes was found to be positively associated with embryo implantation. Moreover, high retardance values, as well as strict criteria of normality in the MS structure, are significantly related to higher embryo implantation numbers and live birth rates.

Keywords

Embryo implantationLive birth rateMeiotic spindlePolarized lightRetardance
Type
Review Article
Information
Zygote , Volume 27 , Issue 1 , February 2019 , pp. 1 - 4
Copyright
© Cambridge University Press 2018 

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