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Fertilization and development of oocytes with separated and conjoined zona pellucida recovered from polyovular follicles: description of two cases and a literature review

Published online by Cambridge University Press:  20 January 2021

Onder Coban Open the ORCID record for Onder Coban [Opens in a new window] ,
Munevver Serdarogullari Open the ORCID record for Munevver Serdarogullari [Opens in a new window] ,
Ruqiya Pervaiz ,
Afet Soykok  and
Hasan Bankeroglu
Onder Coban*
Affiliation:
Department of Embryology, British Cyprus IVF Hospital, Nicosia, Cyprus
Munevver Serdarogullari
Affiliation:
Department of Embryology, British Cyprus IVF Hospital, Nicosia, Cyprus Faculty of Medicine, Cyprus International University, Northern Cyprus via Mersin 10, Turkey
Ruqiya Pervaiz
Affiliation:
Department of Zoology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University,Mardan, Pakistan
Afet Soykok
Affiliation:
Department of Embryology, British Cyprus IVF Hospital, Nicosia, Cyprus
Hasan Bankeroglu
Affiliation:
Department of Gynaecology, British Cyprus IVF Hospital, Nicosia, Cyprus
*
Author for correspondence: Onder Coban. Department of Embryology, British Cyprus IVF Hospital, Dr Bahir Ilter sk. No. 7 Ortakoy Nicosia, Turkish Republic of Northern Cyprus. Tel: +90 533 846 6628. E-mail: ondercoban@yahoo.com
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Summary

Recovery of more than one oocyte from a single follicle during laparoscopic egg collection has been reported sporadically and accepted as confirmation of the presence of polyovular or binovular follicles in the human ovary at reproductive age. Most of these reports include conjoined oocytes that share common or fused zona pellucida, and are generally accepted as evidence for true polyovularity due to its certain characteristics. In this study, we report one case of a conjoined oocyte and another case of the recovery of two separate oocytes in a cumulus cell complex and details of their early embryonic development. To our knowledge, this report of the recovery of two separate oocytes without zonal contact is the first in the literature. We reviewed the relevant literature to evaluate information regarding the origin, incidence and significance of polyovularity in reproductive health.

Keywords

Binovular follicleConjoined oocyteCumulus–oocyte massIn vitro fertilizationTwin eggs
Type
Research Article
Information
Zygote , Volume 29 , Issue 4 , August 2021 , pp. 282 - 285
Copyright
© The Author(s), 2021. Published by Cambridge University Press

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