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Successful birth after ICSI with testicular immotile spermatozoa from a patient with total MMAF in the ejaculates: a case report

Published online by Cambridge University Press:  29 September 2021

Liuguang Zhang Open the ORCID record for Liuguang Zhang [Opens in a new window] ,
Yuhu Li ,
Yuqun Huang  and
Zongqiang Li
Liuguang Zhang*
Affiliation:
Center for Reproductive Medicine, Haikou Mary Hospital, 7 Lantian Road, Haikou570203, China
Yuhu Li
Affiliation:
Center for Reproductive Medicine, Haikou Mary Hospital, 7 Lantian Road, Haikou570203, China
Yuqun Huang
Affiliation:
Dong Guan Guang Ji Hospital, Dong Guan, 523690, China
Zongqiang Li
Affiliation:
College of Animal Science and Technology, Guang Xi University, NanNing 530004, Guang Xi, China
*
Author for correspondence: Liuguang Zhang. Center for Reproductive Medicine, Haikou Mary Hospital, 7 Lantian Road, Haikou570203, China. E-mail: xiaodaoivflab@163.com
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Summary

There has been no report on the outcome of vitrified blastocyst transfer from a vitrified oocyte injected with immotile testicular spermatozoa with only multiple morphological abnormalities of the sperm flagella (MMAF). A couple diagnosed with MMAF returned to the clinic to attempt pregnancy using their vitrified oocytes. Testicular spermatozoa were injected intracytoplasmically, and the following intracytoplasmic sperm injection results were observed. In the second cycle, surplus vitrified oocytes and testicular retrieved sperm were used, but no pregnancy ensued. In the third cycle, a surplus vitrified blastocyst was transferred, and a healthy female child was delivered, with a birth weight of 3050 g and a birth length of 53 cm. In this report we describe a successful pregnancy achieved in a patient presenting MMAF. The successful pregnancy was obtained from vitrified oocytes microinjected with testicular retrieved sperm in a vitrified blastocyst transfer.

Keywords

Multiple morphological abnormalities of the sperm flagellaTesticular spermatozoaVitrified blastocystsVitrified oocytes
Type
Review Article
Information
Zygote , Volume 30 , Issue 2 , April 2022 , pp. 169 - 175
Copyright
© The Author(s), 2021. Published by Cambridge University Press

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Footnotes

*

These authors contributed equally to this work.

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