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From the Editor's desk

Published online by Cambridge University Press:  04 January 2018

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Abstract

Type
From the Editor's desk
Copyright
Copyright © The Royal College of Psychiatrists 2018 

Hope, freedom and new directions in psychiatric research

Publishing power

The New Year begins with a new partnership between the Royal College of Psychiatrists and Cambridge University Press, signalling our shared commitment to excellence in research and scholarship for patient impact. Readers will also have noticed the launch of the Psychiatry Ashes, a friendly competition between the editorial boards of the BJPsych and the Australian & New Zealand Journal of Psychiatry on research impact.Reference Bhui and Malhi1, Reference Malhi and Bhui2 We hope to raise the profile of the use of psychiatric research, and at the same time shed some light on the nature of mental health problems among performers in the sports and arts, and performance in the professions, including psychiatrists, psychologists and mental health carers.

Treatment-resistant mood disorders: call for papers

Treatment-resistant mood disorders continue to be one of the most significant challenges in clinical care; there are significant obstacles to recovery in unipolar depression and comorbid depression with schizophrenia or borderline personality disorder.Reference Gregory, Mallikarjun and Upthegrove3Reference French, Turner, Dawson and Moran8 I am making a call for papers on treatment-resistant mood disorders. How can we better identify the best treatment for specific patient groups, and marshal the multiple emerging novel interventions (neuromodulatory, pharmacological, psychological) alongside repurposing of existing drug and psychological therapies? A summary of the importance of treatment-resistant mood disorders is highlighted in an important analysis by McAllister-Williams et al, which will be published in the journal in 2018.

Please submit your best research on effective interventions by 1 May 2018. We hope to publish the best submissions following peer review in a themed issue in January 2019.

New research

Hope and optimism are essential ingredients of recovery and are included in a new measure of quality of life (Bressan et al, pp. 1–3; Boardman pp. 4–5, Keetharuth et al, pp. 42–49). New screening procedures are proposed for postnatal depression and post-traumatic stress disorder (Howard et al, pp. 50–56; Zammit et al, pp. 11–18). A better understanding is emerging on the phenotypes of 5-hydroxytryptamine mechanisms in Prader–Willi syndrome (Krishnadas et al, pp. 57–58) and developmental coordination disorder (Cunningham et al, pp. 27–33). Electroconvulsive therapy is shown to increase hippocampal and amygdala volumes.

Common innovations in care and therapies that we take for granted are not available globally. A courageous study shows that chaining remains a common practice in a prayer camp in Ghana (Ofori-Atta et al, pp. 34–41). Chaining does not seem to reflect the levels of symptoms, rather stigma and traditions of practice may be driving this practice. The meaning of hope and optimism that we promote in high-income countries are of course deeply inadequate when considering chaining of people with mental illnesses. Ethical and human rights mandates need careful thought (Hughes pp. 9–10; Patel & Bhui, pp. 6–8) and actions that can bring minimum standards of humane care to these venues.

References

1Bhui, KC, Malhi, GS. The Psychiatry Ashes: I can't believe it's not cricket! Br J Psychiatry 2017; 211: 406.Google Scholar
2Malhi, GS, Bhui, K. The psychiatry ashes: it's not cricket! Aust N Z J Psychiatry 2017; 51: 1173–5.Google Scholar
3Gregory, A, Mallikarjun, P, Upthegrove, R. Treatment of depression in schizophrenia: systematic review and meta-analysis. Br J Psychiatry 2017; 211: 198204.Google Scholar
4Akil, H, Gordon, J, Hen, R, et al. Treatment resistant depression: a multi-scale, systems biology approach. Neurosci Biobehav Rev 30 Aug 2017 (doi: 10.1016/j.neubiorev.2017.08.019).Google Scholar
5Zhou, C, Zhang, H, Qin, Y, Tian, T, Xu, B, Chen, J, et al. A systematic review and meta-analysis of deep brain stimulation in treatment-resistant depression. Prog Neuropsychopharmacol Biol Psychiatry 13 Nov 2017 (doi: 10.1016/j.pnpbp.2017.11.012).Google Scholar
6Papadimitropoulou, K, Vossen, C, Karabis, A, Donatti, C, Kubitz, N. Comparative efficacy and tolerability of pharmacological and somatic interventions in adult patients with treatment-resistant depression: a systematic review and network meta-analysis. Curr Med Res Opin 2017; 33: 701–11.Google Scholar
7Gobbi, G, Ghabrash, MF, Nunez, N, Tabaka, J, Di Sante, J, Saint-Laurent, M, et al. Antidepressant combination versus antidepressants plus second-generation antipsychotic augmentation in treatment-resistant unipolar depression. Int Clin Psychopharmacol 2018; 33: 3443.Google Scholar
8French, LRM, Turner, KM, Dawson, S, Moran, P. Psychological treatment of depression and anxiety in patients with co-morbid personality disorder: a scoping study of trial evidence. Personal Ment Health 2017; 11: 101–17.Google Scholar
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