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Serum calcium relative decline as a predictor of post thyroidectomy hypocalcaemia

Published online by Cambridge University Press:  22 October 2024

Hamed Al Maawali Open the ORCID record for Hamed Al Maawali [Opens in a new window]  and
Yahya Al Badaai
Hamed Al Maawali*
Affiliation:
Department of Otolaryngology, Head & Neck Surgery, Armed Forces Hospital, The Medical City for Military & Security Services, Seeb, Governorate of Muscat, Sultanate of Oman
Yahya Al Badaai
Affiliation:
ENT Unit, Department of Surgery, Sultan Qaboos University Hospital, University Medical City, Al Khodh, Muscat, Oman
*
Corresponding author: Hamed Al Maawali; Email: hmad224@hotmail.com
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Abstract

Objectives

To assess the value of corrected calcium decline at 6 hours as a predictor of hypocalcaemia post total thyroidectomy by comparing it to the currently widely used intact parathyroid hormone.

Methods

A retrospective cohort study of patients who underwent total thyroidectomy from January 2016 to February 2020. Serum intact parathyroid hormone and corrected calcium data pre-operatively and 6 hours post-operatively were obtained. Receiver operating characteristic curves were used to compare corrected calcium decline at 6 hours versus 6 hours for relative intact parathyroid hormone decline as predictors of hypocalcaemia, and the area under the curve for each metric was reported.

Results

Patients included in this analysis totalled 209. The receiver operating characteristic analysis suggested that corrected calcium decline at 6 hours has a similar predictive value to 6 hours relative intact parathyroid hormone. The areas under the curves for predicting hypocalcaemia were 0.797 for corrected calcium decline at 6 hours and 0.737 for 6 hours relative intact parathyroid hormone, but the difference (0.06) was not statistically significant.

Conclusions

Our results suggest that corrected calcium decline at 6 hours has a similar predictive value to 6 hours relative intact parathyroid hormone and hence has the potential to predict post-operative hypocalcaemia.

Keywords

hypocalcaemiahypoparathyroidismthyroidectomyparathyroid hormone
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 139 , Issue 2 , February 2025 , pp. 125 - 128
Copyright
Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Hamed Al Maawali takes responsibility for the integrity of the content of the paper

Part of this research was presented at the 11th Emirates Otorhinolaryngology Audiology and Communication Disorders Congress, held as a virtual event 08 April 2021 through 10 April 2021, and at the 17th Annual Meeting of Middle East Academy of Otolaryngology and Head & Neck Surgery, held in The Event Centre, InterContinental Dubai Festival City.

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