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High Frequency of Pseudobacteremia at a University Hospital

Published online by Cambridge University Press:  02 January 2015

J. Russell Little ,
Ellen Trovillion  and
Victoria Fraser
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Abstract

A prospective survey of all positive blood cultures was performed during a 6-month period at a 390-bed, tertiary-care teaching hospital in St Louis, Missouri. Data were collected from the clinical microbiology laboratory, medical records, and physicians caring for patients with positive blood cultures. Of 5,732 blood cultures, 261 (4.6%) were positive, and approximately half of these (51.3%) were categorized as false positive. Positive cultures were significantly more likely to be true positives if obtained from patients with malignancies or if they became positive within the first 48 hours of incubation.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 18 , Issue 3 , March 1997 , pp. 200 - 202
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1997

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References

1. Maki, DG. Through a glass darkly, nosocomial pseudoepidemics and pseudobacteremias. Arch Intern Med 1980;140:26–28.Google Scholar
2. MacGregor, RR, Beaty, HN. Evaluation of positive blood cultures. Arch Intern Med 1972;130:84–87.Google Scholar
3. McGowan, JE. Bacteremia in the hospitalized patient. Arch Intern Med 1977;137:1670.CrossRefGoogle ScholarPubMed
4. Bates, DW, Goldman, L, Lee, TH. Contaminant blood cultures and resource utilization. JAMA 1991;265:365–369.Google Scholar
5. Selwyn, S, Ellis, H. Skin bacteria and skin disinfection reconsidered. Br Med J 1972;1:136–140.CrossRefGoogle ScholarPubMed
6. McCabe, WR, Jackson, GG. Gram-negative bacteremia, I: etiology and ecology. Arch Intern Med 1962;110:847–855.CrossRefGoogle Scholar
7. Strand, CL, Wajsbort, RR, Sturmann, KK. Effect of iodophor vs iodine tincture skin preparation on blood culture contamination rate. JAMA 1993;269:1004–1006.Google Scholar
8. Weinstein, MP, Reller, RB, Murphy, JR, Lichtenstein, KA. The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults, I: laboratory and epidemiologic observations. Rev Infect Dis 1983;5:35–53.Google Scholar
9. Welby, PL, Keller, DS, Storch, GA. Comparison of automated Difco ESP blood culture system with biphasic BBL Septi-Chek system for detection of bloodstream infections in pediatric patients. J Clin Microbiol 1995;33:1084–1088.CrossRefGoogle ScholarPubMed
10. Bates, DW, Cook, EF, Goldman, L, Lee, TH. Predicting bacteremia in hospitalized patients. Arch Intern Med 1990;113:495–500.Google ScholarPubMed