This essay discusses the sundry ethical considerations confronting editors and reviewers. To begin, journal hierarchy and manuscript lifecycles are reviewed. From there, ethical issues faced by individuals in various editorial roles, who interact with various parties, are discussed. Issues include making fair desk rejections, assigning reviewers ethically, refraining from the promotion of HARKing (hypothesizing after results are known), promoting a holistic view of validity, balancing scientific progress with journal success, providing developmental and actionable feedback, disclosing expertise parameters, and upholding the spirit of double-blind review.