The development of mechatronic systems has always been characterized by continuous handling of uncertainties. This challenge, which is associated with dynamic changes in the development context, is increasingly met by companies in the development of physical systems with the implementation of agile approaches in their development processes. However, since established approaches have their origin in software development, they reach various limits in the context of the development of mechatronic systems, e.g. due to the physical properties of the systems. Other features, such as transparent and flexible project management or targeted and early involvement of customers and users in development processes, can also be implemented in mechatronic system development. In order to derive the potentials and limits of existing agile approaches for the context of mechatronic system development, the present paper compares existing approaches with regard to relevant factors from the context of mechatronic system development. The aim is to create a basis for the targeted development, adaptation and use of agile approaches in the field of mechatronic system development.