In this paper, an implantable coplanar waveguide-fed tapered monopole antenna for industrial scientific and medical band (2.4–2.48 GHz) applications is proposed. This proposed design has an overall dimension of 44 × 44 × 0.5 mm3. The designed antenna is made compatible for implantation on human tissues such as skin, fat, or muscles by embedding it on the RT Duroid substrate and the 10 dB return loss bandwidth is 6.12% ranging from 2.35 to 2.5 GHz. This proposed antenna can be significantly used in implantable medical devices and radio frequency (RF), because of its merits such as conformability, flexibility in design and shape, biocompatibility, patient safety, miniaturization, power consumption, etc.