Computer based simulation models are increasingly being used to predict the environmental fate of crop protection chemicals. Some considerations that need to be given in selecting appropriate models for regulatory purposes include model applicability, validation, capability, ease of use, and documentation. Problems commonly encountered in modeling include limited accuracy, lack of defined objectives and standard modeling practices, and misuse of models and results. Models will continue to play an important role in the regulation of crop protection chemicals. It is important that regulators and industry agree on appropriate models and practices, and that regulatory decisions are not based solely on model results but take into account all available data.