Chapter 6 completes the theme of the European Mythology of the Indies (III) and analyzes the impact of Enlightenment thought (French and British) on interpretations of Native Americans and Pacific Islanders. The chapter explores myths of primitivism and progress, showing how appeals to scientific authority grew at the expense of reference to biblical texts. It then examines the impact of the scientific voyages of Bougainville and Cook. On the one hand, the manner and customs of some of the South Seas peoples evoked the same kind of comparisons with classical antiquity as had been made in the Americas, especially the Golden Age of Antiquity, and appeared to offer confirmation of the myth of humankind in its infancy. So it was not just the Polynesians who interpreted the first Europeans in terms of their own myths; the same was true vice versa. On the other hand, the “enlightened” scientific expedition produced new data on non-European peoples which laid the foundations for rethinking theories of development of humankind, whether through progress or degeneration. Increasingly towards the end of the eighteenth century, notions of race became more salient in how non-European peoples were understood.

The third chapter traces the linkages between evolutionary science and aestheticism through the work of popular science writer Grant Allen and the arch aesthete Oscar Wilde, who shared a penchant for socialist politics as well as a firm belief in the truth of both Charles Darwin’s and Herbert Spencer’s evolutionary theories. More importantly, Allen and Wilde were similarly repulsed by the cultural implications of social Darwinism, and for that reason looked to sexual selection – and, by extension, aesthetics – for a life-affirming alternative to the pressures of Darwinian competition. In their fiction and critical prose from the 1880s and 1890s, this chapter argues, both Allen and Wilde eventually arrived at a markedly utopian aesthetics that posited individual self-culture, through the emancipated pursuit of pleasure, as the key to radical social change. This chapter thus sheds light on aestheticism’s late-century polemical turn, which made it a lightning rod in the sexual controversies of the fin de siècle.

Several versions of ‘social Darwinism’ flourished in the late nineteenth and early twentieth century, along with ideologies derived from non-Darwinian evolution theories. They exploited discoveries of fossil hominids including Neanderthals and the Piltdown fraud to construct rival explanations of the emergence of human characteristics that might shape social development. The linear hierarchy of races erected in the nineteenth century remained the basis of many popular accounts, even though professional anthropologists began to turn their backs on it. Ideologies based on national or racial competition were advocated even by writers who did not accept the Darwinian theory of competition within populations. Fear of racial degeneration fuelled the eugenics movement’s calls for the elimination of ‘harmful’ characters, although the input from genetics encouraged an analogy with artificial rather than natural selection.

Richard Wagner’s musical and prose works are shot through with ideas, imagery, and speculation relating to race. Given the influence of racial theorising on almost every area of nineteenth-century European thought and culture, this is hardly surprising. Yet Wagner did not just absorb theories of race: he actively disseminated them, a fact that remains a troubling, if unavoidable part of his legacy. This chapter provides a selective overview of the history of scientific racism in Europe (especially Germany) from the Enlightenment era to the early twentieth century, focusing on the intersections of racial theory with aesthetics, comparative philology, and religious ideologies, including antisemitism. Special attention is devoted to Arthur de Gobineau’s influence on Wagner’s late essays, and the impact of those writings on the Bayreuth Circle, including Houston Stewart Chamberlain.

Osteoarthritis is a common etiology of chronic knee pain and disability associated with aging, weight, and physical inactivity. Global radiographic evidence of knee OA is present in 28.7% of people over 40 years old.Global symptomatic evidence of knee OA is present in 12.4% of people over 40 years old. “Wear and tear” damage to hip joint leading to dysfunctional ECM reorganization leads to chronic onset of pain that is worse with use and associated with decreased knee mobility. Years of conservative treatment with exercise, weight loss, and oral anti-inflammatories can mitigate the disease progression, but severe cases may require intraarticular injections or knee arthroplasty. Some promising injections hope to better manage chronic symptoms by reversing the course of the disease; however, knee arthroplasty remains a gold standard treatment of severe knee OA.

This chapter is the first of three that centre upon Nietzsche’s critique of pessimism in his mature philosophy of the 1880s. It presents Nietzsche’s psychological critique of pessimism as symptomatic of a particular calibration of one’s ‘drives’ that produces fatigue and a world-directed ressentiment. The chapter gives special attention to the crucial similarities and differences between Nietzsche’s psychological reduction of pessimism and those of the degeneration theorists, and the English psychologist James Sully, arguing that Nietzsche’s own position is subtly unique and, in some ways, more plausible. The final sections of the chapter address (1) Nietzsche’s diagnosis of Christianity as the pinnacle manifestation of pessimistic sentiment and (2) the problem of the ‘scope’ of Nietzsche’s psychological reduction.

Before the specter of the Nazi Final Solution, many British intellectuals at the fin de siècle perceived eugenics as forward-thinking and liberating. In their respective novels, A Superfluous Woman (1894) and The Girl from the Farm (1895), the socialist-feminists Emma Frances Brooke and Gertrude Dix paired ideologies of degeneration and eugenics with an endorsement of Edward Carpenter’s ethos of simple living, celebrating good health and wholesomeness. They adopted Francis Galton’s policy of selective breeding yet rejected his promotion of the peerage as “eminent” specimens for propagating future generations. In their fictions, the conservative aristocrat and entitled upper-middle-class man are instead enervated, parasitical decadents and obstacles to social, evolutionary advancement. Ultimately, Brooke’s and Dix’s visions are not altogether unified: whereas Dix simply dismisses her flimsy, immature dandy, Brooke advocates a more radical “negative eugenics” with an eye to her decadent’s diseased offspring. Rejecting privileged, dissipated men in favor of health and liberation, both authors anticipate twenty-first century social critiques of decadence.

The modern era of epilepsy can be said to date from around 1860. In the ensuing decades epilepsy was at the centre of an enormous range of endeavours which included Hughlings Jackson’s landmark works, the theory of cerebral localisation, the introduction of bromide and then phenobarbitone therapy and the first attempts at the surgical resection of the epileptic focus. It was the period when idiopathic epilepsy (‘genuine epilepsy’) was considered to be an inherited degenerative brain disorder, associated with mental symptoms and deficiency and a specific ‘epileptic personality’. It was the period when neurology first became a recognisable medical specialty, special hospitals for epilepsy opened and epilepsy colonies were formed all over the world. Lombroso considered epilepsy and criminality to have close connections. Inpatient treatment was conducted within the asylum system by psychiatrists. Epilepsy was associated with enormous stigma and was widely hidden or denied. In 1911, eugenics was proposed as a solution to the problems caused by epilepsy. Dostoyevsky, Zola, Dickens, Hardy and others included epilepsy in their books, and leading authors suffered from epilepsy but concealed their condition. International medical and psychiatric congresses were held, and during one of these, the International League Against Epilepsy was formed.

Chapter 2 shows how two Elizabethan and Jacobean engagements with problematic multitudes undermined the body politic as a framework for managing multitudes in a context of rapid population growth, economic change and political challenges beyond England. Turning first to growing anxieties about poverty and vagrancy in England, it examines how rogue literature constructed vagrants as a foreign and inherently idle counter-polity, rather than a displaced and degenerated multitude; it then shows how municipal ordinances, surveys and poor laws came to treat the mobile poor as inherently idle of quantification as well as regulation, for whom systematic intervention and routine management was necessary to instill the virtues of industry. Second, it follows late Tudor and early Stuart efforts to undo the degeneration (through mixture with the Irish) of the Old English in Ireland, and to civilize – through projects of plantation, conquest or legal reform – the putatively barbaric Gaelic Irish themselves. In both cases, problematic groups were no longer seen as displaced organs of a body politic but rather as populations that must be made governable in the first instance through policy.

Chapter 5 considers texts in which music acts upon queer bodies to subject them to temporal flux or dislocation. Reading such texts through the lens of both Victorian evolutionary accounts of music’s origins and contemporary theory’s concern with ‘queer temporalities’ makes it possible to better articulate the tropes of backwardness and retrogression that attach to those queer desires awakened by music. In Browning’s ‘Charles Avison’ music’s association with both the evolutionary primitive and sexually abject presents a challenge to the teleological impetus underpinning Victorian ideals of progressive time. Similar motifs also emerge with particular prominence in stories relating to the figure of Pan by Machen, Forster and Benson. Here, the music of Pan unleashes queer desires that act upon bodies to subject them to the reverse flow of evolutionary time. In Forster’s text, Pan’s queerness is also made evident in the narrator’s paranoid fixation with masturbation, revealed in the text’s obsessive patterning of images invoking tactile contact. For Benson, Pan’s music leads his protagonist towards a queer sexual encounter that is simultaneously alluring and horrific.

Chapter four traces the nebulous narrative of degeneration theory in Zola’s La curée, (The Kill) from its origins in medicine to its influence in fiction, and then back to case studies of hermaphrodism. This trajectory reveals how the degeneration diagnosis fundamentally shifted doctor-patient relationships. The French fin-de-siècle natality crisis elevated the stakes of hermaphrodism and non-reproductive sexuality, illustrating how social anxiety can fundamentally alter scientific findings, and how science can, in turn, influence lived experience in fundamental ways. Zola’s obsession with androgyny is merely a partial reflection of what became widespread cultural terror inflected in the writings of numerous authors and doctors, from the well-known Rachilde and Huysmans to the more obscure Armand Dubarry and Dr. Laupts. In La curée, hermaphrodism becomes a scary confluence of scientific, moral, and social anxiety that prefigures its treatment in later nineteenth and early twentieth-century sexology. At the same time, however, Zola’s use of androgyny in La curée unexpectedly subverts his normalizing use of science. By portraying unstable gender identities, La curée undermines the seemingly inexorable calculus of degenerate heredity inherited from medicine and recasts literary naturalism in a new light—less as a derivative of science than as a critic of it.

We explore the inherently racialized premises of colonial–national modernity and of imperial and national archaeologies, juxtaposing them with the contradictions and fluidity inherent in “Greek” and “Israeli” identities. This is followed by a brief critique of the reductionist, and often self-serving, roll-out of ancient DNA studies and of their political co-optation.

Later stories about Raúl, channeling racialized ideas about class, criminality, minority, mental illness, and malingering, suggested that Raúl, as a lower-class Black man, was all but fated to go astray. “Youth” situates the origins of those racialized ideas at the turn of the century, at the height of Argentina’s (overlooked) scientific racism and a broad panic about the “degeneracy” of the lower classes. It was precisely then that the young Raúl himself began his troubles with the law and was placed by his father in a reformatory for unruly boys for over a year (aged 19–21). By tracing Raúl’s experiences with the police, the army, the courts, and reformatory authorities who linked his “degeneracy” to his Blackness, this chapter illustrates how racial narratives, wielded by state and medical agents, began to circumscribe Raúl’s life. The chapter’s key argument is that Raúl’s experiences in this decade, after leaving his parents’ house but before achieving widespread fame, flesh out a key transition in Argentina’s racial narratives between the nineteenth and twentieth centuries: from marking difference primarily along lines of race, to marking difference along lines of class. His trajectory helps illustrate for the first time what it could have meant, in an embodied sense, for Afro-Argentines to “disappear” or amalgamate into a lower class of people racialized by a new, more diffuse form of blackness associated with poverty, marginality, or degeneration rather than strictly with African descent. This early twentieth-century shift in racial narratives in some ways defused the intensity of elites’ gaze upon Afrodescendants and Indigenous people, drawing it toward a wider contingent of lower classes. But the stain of African Blackness and accompanying prejudices did not go away; even as Argentina’s new racial narratives made room for some Afrodescendants to blend into Whiteness (as Raúl’s father, brother, and others did), they came down even more forcefully on people like Raúl who did not conform.

This chapter charts the transition, in British literature of the early twentieth century, from the Decadence associated with Wilde and his generation to the modernism associated with Eliot and his generation. If criticism has readily acknowledged that London, as the locus of an emergent modernist sensibility, was bound up in geographically extended networks of transatlantic and European literary practice, the story of historical transition from Decadence to modernism has been less often told. With particular reference to the poetries of Ezra Pound and T. S. Eliot, the chapter shows how the aesthetics of Decadence were reconfigured and repurposed by modernist writers, before turning in a brief coda to the counter-example of W. B. Yeats, for whom questions of Decadence and modernism were bound up with the national politics of a changing Ireland.

ICSI is a well-established insemination method in IVF due to its overall efficacy and reliability, even when severe male factor is not the main cause of infertility. Although conventional-ICSI provides high fertilization rate, it suffers from some technical drawbacks. Sudden or delayed oocyte degeneration may occur after ICSI even when performed by experienced embryologist and extreme care is applied during the injection phase. Preliminary results from studies conducted in early 2000s suggest that laser-assisted micro-drilling of the zona pellucida before injection (LA-ICSI) may be useful to make ICSI more successful when inseminating oocytes more prone to fertilization failure. Although this condition does not affect many couples, in case of degeneration of all the injected oocytes the IVF cycle must be cancelled. In these cases, LA-ICSI becomes a valuable option that deserves consideration.

Vagrant ‘loafers’ were a preoccupation of novelists and social reformers who saw them as emblematic of social and racial decline during the 1880s and 1890s. This chapter first examines the articles and book-length reports that sought to define and solve the problems of unemployment, inefficiency and vagrancy. These were underwritten by theories of degeneration, social Darwinism and eugenics, ideas that ensured that the vagrant poor were increasingly characterised in ‘scientific’ terms as a biological threat to society and the white ‘imperial’ race. The second half of the chapter examines how this anxiety was expressed in the slum fiction of Arthur Morrison and Margaret Harkness, and in particular how the portrayal of loafers in slum novels and social investigations shaped H. G. Wells’s first dystopia, The Time Machine (1895). Although the influence of social investigation has been noted, Wells’s engagement with the slum novel, and what he perceived to be its failings, has hitherto been overlooked.

How were vagrants represented in the Victorian period? This chapter argues that the Victorians inherited many strategies of representation from the early modern period, including the moral concept of the deserving and undeserving poor, and stereotypes about the lawlessness, deceptiveness and rebelliousness of wanderers and itinerants. But they were also influenced by new epistemologies and ways of knowing. In particular, Victorian representations of vagrancy were influenced by emerging racial theories, such as extinction theory, degeneration theory, social Darwinism and eugenics. This chapter provides an overview of how these theories interlocked with older prejudices and moral frameworks, and in the process introduces the key vagrant archetypes addressed by this study: Gypsies, hawkers, poachers, casual paupers, loafers, pauper immigrants, American Indians, American vagabonds and beachcombers. Together, these figures comprise the taxonomy through which commentators understood, imagined and interpreted vagrancy in the Victorian age.