This study presents a finite element (FE) model of the human hand-arm system to derivenatural frequencies and mode shapes. The FE model is calibrated by considering modalparameters obtained from experimental vibration analyzed by using operational modalanalysis (OMA) and transmissibility. Modal and harmonic analyses of the FE model areperformed for two boundary conditions. The first one considers fixed shoulder conditionwhile the second one introduces the trunk in order to permit motion of the shoulder. Theresults show that the natural frequencies of the second model that permits shoulder motionare comparable with those determined from measurements. Especially, the natural frequencyabout 12 Hz, which is corresponding to the frequency of maximum weight in ISO-5349-1(2001), is not present in the model with fixed shoulder condition, while it appears in thesecond model. The results of the present study suggest that improved finite element modelsof the human hand-arm system may reveal hand-arm injury mechanism, the understanding ofwhich may assist in deriving appropriate frequency weightings for the assessment ofdifferent components of the hand-arm vibration syndrome.