In this work we introduce a stochastic model for the spread of a virus in a cell population where the virus has two ways of spreading: either by allowing its host cell to live and duplicate, or by multiplying in large numbers within the host cell, causing the host cell to burst and thereby let the virus enter new uninfected cells. The model is a kind of interacting Markov branching process. We focus in particular on the probability that the virus population survives and how this depends on a certain parameter λ which quantifies the ‘aggressiveness’ of the virus. Our main goal is to determine the optimal balance between aggressive growth and long-term success. Our analysis shows that the optimal strategy of the virus (in terms of survival) is obtained when the virus has no effect on the host cell's life cycle, corresponding to λ = 0. This is in agreement with experimental data about real viruses.

Examining possibilities for the coexistence of two competing populations is a classic problem which dates back to the earliest ‘predator-prey’ models. In this paper we study this problem in the context of a model introduced in Björnberg et al. (2012) for the spread of a virus infection in a population of healthy cells. The infected cells may be seen as a population of ‘predators’ and the healthy cells as a population of ‘prey’. We show that, depending on the parameters defining the model, there may or may not be coexistence of the two populations, and we give precise criteria for this.

File-sharing networks are distributed systems used to disseminate files among nodes of a communication network. The general simple principle of these systems is that once a node has retrieved a file, it may become a server for this file. In this paper, the capacity of these networks is analyzed with a stochastic model when there is a constant flow of incoming requests for a given file. It is shown that the problem can be solved by analyzing the asymptotic behavior of a class of interacting branching processes. Several results of independent interest concerning these branching processes are derived and then used to study the file-sharing systems.