In this volume Anthi Andronikou explores the social, cultural, religious and trade encounters between Italy and Cyprus during the late Middle Ages, from ca. 1200 -1400, and situates them within several Mediterranean contexts. Revealing the complex artistic exchange between the two regions for the first time, she probes the rich but neglected cultural interaction through comparison of the intriguing thirteenth-century wall paintings in rock-cut churches of Apulia and Basilicata, the puzzling panels of the Madonna della Madia and the Madonna di Andria, and painted chapels in Cyprus, Lebanon, and Syria. Andronikou also investigates fourteenth-century cross-currents that have not been adequately studied, notably the cult of Saint Aquinas in Cyprus, Crusader propaganda in Santa Maria Novella in Florence, and a unique series of icons crafted by Venetian painters working in Cyprus. Offering new insights into Italian and Byzantine visual cultures, her book contributes to a broader understanding of cultural production and worldviews of the medieval Mediterranean.