During the last glacial maximum (LGM), glaciers existed in scattered mountainous locations in central Europe between the major ice masses of Fennoscandia and the Alps. A positive degree-day glacier mass-balance model is used to constrain paleo-climate conditions associated with reconstructed LGM glacier extents of four central European upland regions: the Vosges Mountains, the Black Forest, the Bavarian Forest, and the Giant Mountains. With reduced precipitation (25–75%), reflecting a drier LGM climate, the modeling yields temperature depressions of 8–15°C. To reproduce past glaciers more severe cooling is required in the west than in the east, indicating a strong west–east temperature anomaly gradient.