This study examines Nigeria’s National Information Technology Development Agency Code of Practice for Interactive Computer Service Platforms as one of Africa’s first push towards digital and social media co-regulation. Already established as a regulatory practice in Europe, co-regulation emphasises the need to impose duties of care on platforms and hold them, instead of users, accountable for safe online experiences. It is markedly different from the prior (and existing) regulatory paradigm in Nigeria, which is based on direct user regulation. By analysing the Code of Practice, therefore, this study considers what Nigeria’s radical turn towards co-regulation means for digital policy and social media regulation in relation to standards, information-gathering, and enforcement. It further sheds light on what co-regulation entails for digital regulatory practice in the wider African context, particularly in terms of the balance of power realities between Global North platforms and Global South countries.