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2 results

  • Outcome of inpatient opiate detoxification treatment in immigrants as compared to native Germans

  • M. Specka, A. Buchholz, T. Kuhlmann, C. Haasen, N. Scherbaum
  • Journal:
    European Psychiatry / Volume 25 / Issue 4 / May 2010
    Published online by Cambridge University Press:
    16 April 2020, pp. 242-248
  • Background

    Immigration is a factor with effects on the course of substance abuse and treatment response, however there is little consistent data regarding outcome of inpatient opiate detoxification treatment in immigrants as compared to native patients.

    Methods

    Patient history and the success of current detoxification treatment were systematically documented in a multicenter study in Germany which included 10 psychiatric hospitals with specialized detoxification wards.

    Results

    Out of 893 patients, 240 (27%) had a migration history. We further analyzed the three main groups (German, n = 653; Turkish, n = 58; Russian origin, n = 103). There were significant differences between groups regarding sociodemographic data, drug history, treatment experience and success of current treatment. However, considering the younger age of patients with Russian origin, analysis of younger patients (< 31 years) detected only minor group differences. In multiple logistic regressions age and center showed statistically significant associations with all outcome variables (early dropout, achievement of drug-free urine screen, regular completion of detoxification treatment, and referral to further treatment), while (Russian) origin was associated only with premature termination of treatment.

    Conclusion

    Young men were the main problem group regardless of origin. Significant center effects raise doubts regarding results from monocenter research.

  • The use of naltrexone, an opiate antagonist, in the treatment of opiate addiction

  • Conor K Farren
  • Journal:
    Irish Journal of Psychological Medicine / Volume 14 / Issue 1 / March 1997
    Published online by Cambridge University Press:
    13 June 2014, pp. 31-34
    Print publication:
    March 1997

  • Objective: The objective of this article is to review the use of the opiate antagonist naltrexone as an alternative to opiate agonist maintenance in the treatment of opiate addiction.

    Method: An extensive literature search, via Medline, Biosis, Psycinfo and other databases was carried out.

    Results: Naltrexone has been used in the treatment of opiate addicts in a variety of settings. A number of methods of induction onto naltrexone of recently abstinent addicts have been used in different settings. Naltrexone has had a wide range of outcome success with different populations and associated treatment regimes.

    Conclusions: The benefits of naltrexone can be compared with alternatives such as methadone maintenance and therapeutic communities. Naltrexone can be made more effective in the general population of opiate addicts with the use of adjunctive therapies.