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There is a significant relation between old-age depression and subsequent dementia in patients aged 50. This supports the hypothesis of old-age depression being a predictor, and possibly a causal factor, of subsequent dementia. The number of people aged 60 years and over has tripled since 1950, reaching 16% in 2050, leading to new medical challenges. Depression is the most common mental disorder in older adults, affecting 7% of the older population. Dementia is the second most common with about 5% prevalence worldwide, but it is the first leading cause of disease burden.
Objectives
Early detection and treatment is essential in promoting remission, preventing relapse, and reducing emotional burden. Speech is a well established early indicator of cognitive deficits. Speech processing methods offer great potential to fully automatically screen for prototypic indicators of both dementia and depressive disorders.
Methods
We present two different methods to detect pathological speech with artificial neural networks. We use both deep architectures, as well as more traditional machine learning approaches.
Results
The models developed using a two-stage deep architecture achieved 59% classification accuracy on the test set from DementiaBank. Our CNN system achieved the best classification accuracy of 63.6% for dementia, but reaching 70% for depressive disorders on the test set from Distress Analysis Interview Corpus.
Conclusions
These methods offer a promising classification accuracy ranging from 63% to 70%, applicable in an innovative speech-based screening system.
Chapter Seven discusses scholars’ long-standing debates about what the divisions marked by the disjunctive accents represent linguistically. They offer at least three primary suggestions, all of which have validity: 1) to mark stress, 2) to provide musical notations, and 3) to express syntax. Thus, the linguistic representation of the divisions marked by the disjunctive accents is examined from the word level through the sentence level and some related topics, specifically prosodic analysis of the accentual divisions and performance structure are also discussed. This chapter demonstrates that the divisions marked by the Tiberian accents correspond with prosodic divisions and suggested three criteria for delimitation: 1) major disjunctive accents (Silluq, Athnach, Little Zaqeph, Rebia, and rarely Segolta) function as major delimiters, 2) final disjunctives have no dividing force, and 3) a disjunctive accent on the initial word in a phrase or a sentence does not have dividing force. Notably, these accentual divisions correspond with performance structure in light of pausal duration on speech. This shows that the primary purpose of the accents is to mark the proper recitation of the text.
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