The validity and reliability of a new ambulatory impedance
cardiograph (AZCG) was tested against the Minnesota Impedance
Cardiograph (ZCG) during rest, orthostasis, and mental
stress. Impedance cardiography allows noninvasive assessment
of stroke volume, cardiac output, and systolic time intervals.
A reliable ambulatory device would allow studies outside
the lab. The devices were compared at two sites in healthy
subjects. In both studies, the AZCG tracked changes across
conditions closely with the ZCG (all Period × Device
interactions were nonsignificant). Pearson rs,
were .65 to .93, random intraclass correlation coefficients
ranged from .80 to .98, indicating high degrees of shared
measurement variance, and Cronbach's alpha indicated
very good internal reliabilities (.91 to .99). Relative
to the ZCG, the new AZCG appears to provide valid and reliable
estimates of cardiac function at rest and during behavioral
challenges in the lab.