Field experiments were conducted from 1985 to 1987 to evaluate herbicide systems for minimum-tillage and conventional-tillage peanut production. While acceptable weed control could be achieved in both tillage systems, minimum-tillage systems generally had to be more herbicide intensive. Preemergence or preplant-incorporated within-the-row applications of either ethalfluralin or pendimethalin plus postemergence applications of paraquat and sethoxydim provided Texas panicum control equivalent to preplant-incorporated applications of ethalfluralin or pendimethalin. Early-postemergence paraquat applications improved Florida beggarweed and pitted morningglory control in conventional-tillage systems at least 15% compared to the same systems without paraquat Control of bristly starbur and sicklepod in conventional-tillage systems did not increase with paraquat application. Broadleaf weed control did not differ between tillage systems, except pitted morningglory control was lower in the minimum-tillage system. Conventional-tillage peanuts produced yields 800 to 1900 kg/ha higher, depending on herbicide system, and also provided greater net returns than minimum-tillage peanuts. The greater yield and net returns in conventional- versus minimum-tillage systems were not attributed to weed control or disease problems.