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1 results

  • 5 - The Ethics of Pediatric Research

  • Edited by Geoffrey Miller , Yale University, Connecticut
  • Book:
    Pediatric Bioethics
    Published online:
    07 May 2010
    Print publication:
    23 November 2009, pp 54-72

  • Summary

    Pediatric research ethics is based on respect for children and their best interests. The purpose of biomedical research is to contribute to knowledge, but this laudable goal may put children at risk of harm in clinical research, potentially stripping them of their rights and the respect they deserve. Pediatric research ethics relies on this respect, sometimes at the expense of knowledge that could benefit society. Pediatric medicine became thoroughly recognized in the 19th century, leading to the creation of pediatric hospitals. Two central figures in the pediatric research ethics debate included Paul Ramsey and Richard McCormick. The Common Rule instructs institutional review boards (IRBs) to ensure that the risks to subjects are minimized and that these risks carry reasonably equal weight in relation to the anticipated benefits. Knowledge gained from research must be obtained in a way that recognizes the vulnerability of children and respects their best interests.