Field studies in 1990 and 1991 at six locations in Georgia and one location in North Carolina evaluated AC 263,222 for weed control, peanut tolerance, and yield. AC 263,222 applied early postemergence at 71 g ai ha−1 controlled bristly starbur, coffee senna, common lambsquarters, Ipomoea species, prickly sida, sicklepod, smallflower morningglory, and yellow nutsedge at least 91%. AC 263,222 controlled common cocklebur 77% and Florida beggarweed from 47 to 100%. Crop injury was 4% for AC 263,222 applied once and 12% or less from two applications. Mixtures of bentazon with AC 263,222 did not improve control compared to AC 263,222 alone. Imazethapyr did not improve control of AC 263,222 systems. In several locations, bentazon reduced control of Florida beggarweed with AC 263,222 when applied in a mixture compared to AC 263,222 alone. Weed control from the standard of paraquat plus bentazon applied early postemergence followed by paraquat, bentazon plus 2,4-DB applied POST did not provide the level or spectrum of weed control as AC 263,222 systems.